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Caspofungin

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162808-62-0 Basic informationMore
USE
C<sub>max</sub> 70 mg 1-h infusion: c. 10 mg/L 1 h post infusion<br/> Plasma half-life: 9–11 h<br/> Volume of distribution: 0.15 L/kg<br/> Plasma protein binding: 97%<br/> Blood concentrations increase in proportion to dosage.<br /> <strong>Distribution </strong><br /> The drug is widely distributed, the highest concentrations being found in the liver. Levels in the CSF are negligible.<br /> <strong>Metabolism and excretion</strong><br /> It is slowly metabolized by the liver through non-enzymatic peptide hydrolysis and N-acetylation, and the two inactive metabolites are excreted in the feces and bile. No dosage adjustment is required in patients with renal impairment; however, a dose reduction to 35 mg following the 70 mg loading dose is recommended for patients with moderate hepatic impairment. Caspofungin is not cleared by hemodialysis.
Lastest Price from Caspofungin manufacturers
  • Caspofungin
  • US $0.00-0.00/Kg/Drum
  • CAS:162808-62-0
  • Min. Order: 1KG
  • Purity: 98%min
  • Supply Ability: 500kg
  • 2024-09-18
  • Caspofungin
  • US $0.00-0.00/KG
  • CAS:162808-62-0
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 500KG
  • 2024-08-26

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  • Company Name:Hangzhou Yuhao Chemical Technology Co., Ltd
  • Tel:0571-82693216
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  • Company Name:Nanjing Sunlida Biological Technology Co., Ltd.
  • Tel:025-57798810
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    Purity:99% Package:1g;5g;25g;100g Remarks:SLD-1896 More...
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