Blonanserin

• Product Name:Blonanserin
• Synonyms: 6-broMo-4,8-dichloro-5-Methoxyquinoline Blonansarin – Blonanserin, AD-5423, Lonasen Blonanserin-d8 HCl CYCLOOCTA[B]PYRIDINE, 2-(4-ETHYL-1-PIPERAZINYL)-4-(4-FLUOROPHENYL)-5,6,7,8,9,10-HEXAHYDRO- Blonanserin AD 5423 2-(4-Ethyl-1-piperazinyl)-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine
• CAS:132810-10-7
• MF:C23H30FN3
• MW:367.5
• EINECS:
• Mol File:132810-10-7.mol
• 

Blonanserin, a dual antagonist of dopamine D2 and serotonin 5-HT2 receptors, was launched past year in Japan for the oral treatment of psychosis and schizophrenia. It is the latest entry in the class of atypical antipsychotic agents to reach the market. Blonanserin exhibits high affinity for D2 and 5-HT2 receptors (IC50 23.6 and 9.85 nM, respectively). Its affinity for D2 receptors is very close to that of haloperidol and risperidone, whereas the affinity for 5-HT2 receptors is about 7 times higher than that of haloperidol and 10 times lower than that of risperidone.Blonanserin is chemically derived in three steps starting with a polyphosphoric acid mediated condensation reaction of cyclooctanone with 4-fluorobenzoylacetonitrile. The resultant 4-fluorophenylcycloocta[b]pyridin-2-one intermediate is converted to the corresponding 2-chloro derivative by treatment with phosphoryl chloride and subsequently condensed with 1-ethylpiperazine to afford blonanserin.

• Blonanserin
• 
• US $50.00 /kg
• CAS:132810-10-7
• Min. Order: 1kg
• Purity: 99%
• Supply Ability: 50
• 2024-02-27

• Blonanserin
• 
• US $15.00-10.00/KG
• CAS:132810-10-7
• Min. Order: 1KG
• Purity: 99%+ HPLC
• Supply Ability: Monthly supply of 1 ton
• 2021-07-13

• Company Name:Zhuhai Yourun Co., Ltd.
• Tel:0756-6811852 13923369215
• Products Intro:Product Name:Blonanserin
  CAS:132810-10-7
  Purity:99 Package:5KG;1KG More...
• CB Index:55
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• Company Name:SiChuang NanBu Honesty Technology Co., Ltd.
• Tel:0838-5675166 15883665058
• Products Intro:CAS:132810-10-7
  Purity:>=99.5% More...
• CB Index:55
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• Company Name:J & K SCIENTIFIC LTD.
• Tel:010-82848833 400-666-7788
• Products Intro:Product Name:Blonanserin, 99.5%, a D2/5-HT2 receptor antagonist
  CAS:132810-10-7
  Purity:99.5% Package:1G;250MG;5G More...
• CB Index:76
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• Company Name:Chembest Research Laboratories Limited
• Tel:021-20908456
• Products Intro:Product Name:Blonanserin
  CAS:132810-10-7
  Remarks:C13387 More...
• CB Index:61
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• Company Name:TCI (Shanghai) Development Co., Ltd.
• Tel:021-67121386
• Products Intro:Product Name:Blonanserin
  CAS:132810-10-7
  Purity:98.0 Package:780RMB/25MG More...
• CB Index:81
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• Company Name:Adamas Reagent, Ltd.
• Tel:400-6009262 16621234537
• Products Intro:Product Name:Blonanserin
  CAS:132810-10-7
  Purity:对照品 Package:10mg~500mg Remarks:AC000523000
• CB Index:59
• Related Information:Catalog(14113)