Daptomycin
103060-53-3 Basic informationMore
- Product Name:Daptomycin
- Synonyms: N-[N-Decanoyl-L-Trp-D-Asn-L-Asp-]-cyclo[Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-methyl-L-Glu-]-3-(2-aminobenzoyl)-L-Ala-] N-(1-Oxodecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithinyl-L-α-aspartyl-D-alanyl-L-α-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-α,2-diamino-γ-oxo-benzenebutanoicacid(13-4)lactone DAPTOMYCINE Dapcin Daptomycin, >=99% Daptomycin Ready Made Solution CUBICIN DAPTOMYCIN Cidecin
- CAS:103060-53-3
- MF:C72H101N17O26
- MW:1620.67
- EINECS:600-389-2
- Mol File:103060-53-3.mol
USE
Healthy volunteers were administrated (intravenous injection) of six different doses in the range of 0.5~6.0 mg/kg and 1.0 mg/kg 14C marked daptomycin, the results showed that daptomycin has a relatively long T1/2 in vivo (T1/2 = 6~8 h), a relatively small volume of distribution (V = 0.1~0.2 L/kg), and a renal clearance CLr of 0.17~0.2 ml/(min?kg). Daptomycin is mainly presented in the blood in the form of non-metabolized original drug with kidney as the major metabolic organ. About 78% of daptomycin is excreted in the urine. There are metabolites of daptomycin presented in the urine. The distribution pattern of daptomycin in the body is not fully understood. Patients of septicemia and endocarditis needs to subject to intravenous administration of daptomycin at a dose of 3mg/kg in every 12 h. Compared with healthy volunteers, people in daptomycin group had a average peak blood concentration (cmax): 35.45, which is lower than in healthy people. They also had an increased steady-state volume of distribution (Vss = 0.21) and a 22% increased clearance rate (CL).
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- Daptomycin
- US $0.00-0.00/Kg/Drum
- CAS:103060-53-3
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 1000kg
- 2024-12-13
- Daptomycin
- US $80.70 /KG
- CAS:103060-53-3
- Min. Order: 10KG
- Purity: 99%
- Supply Ability: 10000kg
- 2024-10-11
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- Company Name:Shanghai Linka Biotechnology Co., Ltd.
- Tel: 15901858719
- Products Intro:Product Name:Daptomycin
CAS:103060-53-3
Purity:0.95 Package:10g;100g;1kg;5kg;25kg Remarks:10g;100g;1kg;5kg;25kg More... - CB Index:55
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- Company Name:Shanghai Minkai Biological Technology Co., Ltd
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Purity:99% HPLC Package:1g;1kg;10kg - CB Index:58
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- Company Name:Hubei widely chemical technology Co., Ltd.
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CAS:103060-53-3
Purity:95% 外观: 黄色或淡黄色粉末,品牌:湖北威德利,常规现货库存欢迎咨询张军 Package:1g/RMB 500;10g/RMB 375;100g/RMB 235 More... - CB Index:64
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- Company Name:Hangzhou Zhongmeihuadong Pharmaceutical Jiangdong Co., Ltd.
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- Company Name:Jiangxi ravel Biotechnology Co.,Ltd
- Tel:400-880-2824; 13184580281
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- Company Name:J & K SCIENTIFIC LTD.
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- Company Name:Chemvon Biotechnology Co., Ltd
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