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Allyl alcohol

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The toxicity of allyl alcohol is moderatelyhigh, affecting primarily the eyes. Theother target organs are the skin andrespiratory system. Inhalation causes eyeirritation and tissue damage. A 25-ppmexposure level is reported to produce asevere eye irritation. It may cause atemporary lacrimatory effect, manifested byphotophobia and blurred vision, for somehours after exposure. Occasional exposureof a person to allyl alcohol does notindicate chronic or cumulative toxicity.Dogterom and associates (1988) investigatedthe toxicity of allyl alcohol in isolated rathepatocytes. The toxicity was independent oflipid peroxidation, and acrylate was found tobe the toxic metabolite<br/>Ingestion of this compound may causeirritation of the intestinal tract. The oral LD50value in rats is 64 mg/kg (NIOSH 1986)..

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