Halothane
151-67-7 Basic informationMore
- Product Name:Halothane
- Synonyms: 1,1,1-Trifluoro-2-bromo-2-chloroethane 1,1,1-Trifluoro-2-chloro-2-bromoethane HALOTHANE 2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE 1-BROMO-1-CHLORO-2,2,2-TRIFLUOROETHANE Halothane (1 mL) 2-Bromo-1,1,1-trifluoroethane-2-chloro- 2-Bromo-2-chloro-1,1,1-trifluoroethane, Halothane
- CAS:151-67-7
- MF:C2HBrClF3
- MW:197.38
- EINECS:205-796-5
- Mol File:151-67-7.mol
USE
Halothane is a nonflammable, nonpungent, volatile, liquid,halogenated (F, Cl, and Br) ethane (bp=50°C), introducedin 1956. Halothane may increase heart rate, cause cardiacarrhythmias, increase cerebral blood flow, and increase intracranialpressure.It can undergo spontaneous oxidationwhen exposed to ultraviolet light to yield HCl, HBr, Cl ,Br<sup>-</sup> , and phosgene (COCl<sub>2</sub>). To prevent oxidation it ispackaged in amber bottles with a low concentration of thymol(0.01%) as a stabilizer. The drug has a high potency(MAC=0.75%), a blood:gas partition coefficient of 2.4,and high adipose solubility. Halothane undergoes both reductiveand oxidative processes with up to 20% of the doseundergoing metabolism .The trifluoroacetylchloride metabolite is electrophilic and can form covalentbonds with proteins leading to immune responses andhalothane hepatitis upon subsequent halothane exposure.Halothane hepatitis is rare with 1 case reported for every6,000 to 35,000 patients exposed.
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:Halothane
CAS:151-67-7
Package:10g,1g,50g More... - CB Index:76
- Related Information:Catalog(94657)
- Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel:021-61259108 18621169109
- Products Intro:Product Name:2-BroMo-2-chloro-1,1,1-trifluoroethane
CAS:151-67-7
Purity:97% Remarks:AAM124957 More... - CB Index:62
- Related Information:Catalog(40228)
- Company Name:Energy Chemical
- Tel:021-021-58432009 400-005-6266
- Products Intro:Product Name:2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE
CAS:151-67-7
Purity:99% Package:100g,25g More... - CB Index:61
- Related Information:Catalog(44689)
- Company Name:Shanghai Hanhong Scientific Co.,Ltd.
- Tel:021-54306202 13764082696
- Products Intro:Product Name:2-Bromo-2-chloro-1,1,1-trifluoroethane
CAS:151-67-7
Purity:98% Remarks:B12030 More... - CB Index:64
- Related Information:Catalog(42958)