Amodiaquine
86-42-0 Basic informationMore
- Product Name:Amodiaquine
- Synonyms: 4-((7-chloro-4-quinolyl)amino)-alpha-(diethylamino)-o-creso 4-((7-Chloro-4-quinolyl)amino)-alpha-(diethylamino)-o-cresol 4-[(7-Chloro-4-quinolinyl)amino]-alpha-(diethylamino)-o-cresol 7-Chloro-4-(3-diethylaminomethyl-4-hydroxyphenylamino)quinoline Amodiaquine, ring-closed CAM-AQ1 CAM-AQI Camochin
- CAS:86-42-0
- MF:C20H22ClN3O
- MW:355.86
- EINECS:201-669-3
- Mol File:86-42-0.mol
-
USE
Amodiaquine, an antimalarial agent related to chloroquine, was
introduced over 40 years ago for the treatment and prophylaxis of malaria. The
drug was voluntarily withdrawn in the United Kingdom in 1975 for commercial
reasons but was subsequently reintroduced in 1985 to meet the medical demand
for an antimalarial drug to deal with the rapid spread of chloroquine-resistant
falciparum malaria in Asia and Africa. By 1986 a significant number of cases of
agranulocytosis associated with prophylactic use, some of which were fatal, had
been reported there and it has been estimated that the frequency of this risk is of
the order of 1:2,000. Although most cases occurred when amodiaquine had been
used in combination with other antimalarials, the major manufacturer decided to
withdraw the prophylactic indication worldwide following discussions with experts.
Preparations remain available for the treatment of acute attacks of malaria which
involves only a short period of exposure to the drug.
(Reference: (WHODI) WHO Drug Information, 1, 5, 1987)
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- Company Name:Chengdu Saint - Kay Biotechnology Co., Ltd.
- Tel:028-85157043 15882256948
- Products Intro:Product Name:Amodiaquine
CAS:86-42-0
Purity:98% Package:MG G More... - CB Index:58
- Related Information:Catalog(4391)
- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:AModiaquine
CAS:86-42-0
Package:100Mg,10Mg More... - CB Index:76
- Related Information:Catalog(94657)
- Company Name:Hangzhou Yuhao Chemical Technology Co., Ltd
- Tel:0571-82693216
- Products Intro:Product Name:aModiaquine
CAS:86-42-0
More... - CB Index:52
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- Company Name:ChemStrong Scientific Co.,Ltd
- Tel:0755-0755-66853366 13670046396
- Products Intro:Product Name:Amodiaquine
CAS:86-42-0
Purity:95% HPLC Package:10mg;25mg;50mg;100mg More... - CB Index:56
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- Company Name:Shanghai EFE Biological Technology Co., Ltd.
- Tel:021-65675885 18964387627
- Products Intro:Product Name:Amodiaquin-d10
CAS:86-42-0
Purity:98% Package:1mg;2mg;5mg - CB Index:58
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