Amodiaquine
86-42-0 Basic informationMore
- Product Name:Amodiaquine
- Synonyms: 4-((7-chloro-4-quinolyl)amino)-alpha-(diethylamino)-o-creso 4-((7-Chloro-4-quinolyl)amino)-alpha-(diethylamino)-o-cresol 4-[(7-Chloro-4-quinolinyl)amino]-alpha-(diethylamino)-o-cresol 7-Chloro-4-(3-diethylaminomethyl-4-hydroxyphenylamino)quinoline Amodiaquine, ring-closed CAM-AQ1 CAM-AQI Camochin
- CAS:86-42-0
- MF:C20H22ClN3O
- MW:355.86
- EINECS:201-669-3
- Mol File:86-42-0.mol
-
USE
Amodiaquine, an antimalarial agent related to chloroquine, was
introduced over 40 years ago for the treatment and prophylaxis of malaria. The
drug was voluntarily withdrawn in the United Kingdom in 1975 for commercial
reasons but was subsequently reintroduced in 1985 to meet the medical demand
for an antimalarial drug to deal with the rapid spread of chloroquine-resistant
falciparum malaria in Asia and Africa. By 1986 a significant number of cases of
agranulocytosis associated with prophylactic use, some of which were fatal, had
been reported there and it has been estimated that the frequency of this risk is of
the order of 1:2,000. Although most cases occurred when amodiaquine had been
used in combination with other antimalarials, the major manufacturer decided to
withdraw the prophylactic indication worldwide following discussions with experts.
Preparations remain available for the treatment of acute attacks of malaria which
involves only a short period of exposure to the drug.
(Reference: (WHODI) WHO Drug Information, 1, 5, 1987)
Lastest Price from Amodiaquine manufacturers
- Amodiaquine
-
- US $1.10 /g
- CAS:86-42-0
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons Min
- 2021-06-18
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- Company Name:Chengdu Saint - Kay Biotechnology Co., Ltd.
- Tel:028-85157043 15882256948
- Products Intro:Product Name:Amodiaquine
CAS:86-42-0
Purity:98% Package:MG G More... - CB Index:58
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:AModiaquine
CAS:86-42-0
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- Company Name:Hangzhou Yuhao Chemical Technology Co., Ltd
- Tel:0571-82693216
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CAS:86-42-0
More... - CB Index:52
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- Company Name:Nanjing Norris-Pharm Technology Co., Ltd
- Tel: 13901585132
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CAS:86-42-0
Purity:0.95 Package:5KG;1KG;100G - CB Index:55
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- Company Name:Nanjing Sunlida Biological Technology Co., Ltd.
- Tel:025-57798810
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CAS:86-42-0
More... - CB Index:55
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- Company Name:TargetMol Chemicals Inc.
- Tel:021-33632979 15002134094
- Products Intro:Product Name:Amodiaquine
CAS:86-42-0
Package:1 mL;10 mg;100 mg;2 mg;25 mg;5 mg;50 mg - CB Index:58
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