Ebastine
90729-43-4 Basic informationMore
- Product Name:Ebastine
- Synonyms: 4'-(1,1-Dimethylethyl)-γ-[4-(diphenylmethoxy)piperidin-1-yl]butyrophenone 4'-tert-Butyl-γ-[4-(diphenylmethoxy)piperidino]butyrophenone Ebastel-OD LAS-90 IMp. A (EP): DiphenylMethanol (Benzhydrol) Ebastine Impurity 1-butanone,1-(4-(1,1-dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidiny 4’-tert-butyl-4-(4-(diphenylmethoxy)piperidino)butyrophenone
- CAS:90729-43-4
- MF:C32H39NO2
- MW:469.66
- EINECS:635-609-6
- Mol File:90729-43-4.mol
-
USE
Ebastine belongs to an effective second generation histamine H1 receptor antagonist. One important property of it is that it doesn’t penetrate the blood brain barrier. Therefore, it is capable of blocking the H1 receptor in peripheral tissue without having some specific side effects such as sedation and drowsiness. Ebastine is mainly applied for the treatment of allergic rhinitis, pruritus as well as acting as an alternative drug in Decongestant. Upon entering into the human body, it can subject to the action of hepatic cytochrome P450 3A4 to be converted to an active carboxylic acid metabolite, carebastine. The later one is the major active form in vivo. Under certain range, it can inhibit T cell proliferation and the production of Th2-type pro-inflammatory cytokines through macrophages. Ebastine generally has a high safety property without causing cognitive/psychomotor impairment and sedation, like placebo. However, it can cause side effects such as inflammation of the air-cavities around nose, sore throat, indigestion, nausea, headache, and abdominal pain.
Lastest Price from Ebastine manufacturers
- Ebastine
-
- US $0.00-0.00/Kg/Drum
- CAS:90729-43-4
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 1000KG
- 2024-12-13
- Ebastine
-
- US $1.00-1.00/KG
- CAS:90729-43-4
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 50tons
- 2024-11-05
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- Company Name:wuhan dingxingtong Chemical Technology Co., Ltd Co., Ltd
- Tel:027-59207796 13429867250
- Products Intro:Product Name:Ebastine
CAS:90729-43-4
Purity:99% Package:1KG;5KG;10KG - CB Index:58
- Related Information:Catalog(1989)
- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:Ebastine
CAS:90729-43-4
Purity:98.0%(LC&T) Package:1G,5G More... - CB Index:76
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- Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel:021-61259108 18621169109
- Products Intro:Product Name:Ebastine
CAS:90729-43-4
Purity:>98.0%(LC)(T) Package:1g;5g Remarks:E0925 More... - CB Index:62
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- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:Ebastine
CAS:90729-43-4
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
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- Company Name:Chembest Research Laboratories Limited
- Tel:+86-21-20908456
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CAS:90729-43-4
Remarks:C13601 More... - CB Index:61
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- Company Name:TCI (Shanghai) Development Co., Ltd.
- Tel:021-67121386
- Products Intro:Product Name:Ebastine
CAS:90729-43-4
Purity:98.0% LC&T Package:1G,5G More... - CB Index:81
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- Company Name:Energy Chemical
- Tel:021-021-58432009 400-005-6266
- Products Intro:Product Name:Ebastine
CAS:90729-43-4
Purity:98% Package:5G,1G More... - CB Index:61
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