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CHLORDIAZEPOXIDE HYDROCHLORIDE

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USE
Chlordiazepoxide hydrochloride, 7-chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepine4-oxide monohydrochloride (Librium), is well absorbedafter oral administration. Peak plasma levels are reachedin 2 to 4 hours. The half-life of chlordiazepoxide is 6 to30 hours. N-demethylation and hydrolysis of the condensedamidino group are rapid and extensive, producing demoxepamas a major metabolite. Demoxepam can undergo fourdifferent metabolic fates. It is converted principally to itsactive metabolite nordazepam, which is also a major activemetabolite of diazepam, clorazepate, and prazepam.Nordazepam, in turn, is converted principally to active oxazepam(marketed separately), which conjugated to the excretedglucuronide. Because of the long half-life of parentdrug and its active metabolites, this drug is long acting andself-tapering. As with diazepam (vide infra), repeated administrationof chlordiazepoxide can result in accumulationof parent drug and its active metabolites, and thus cause excessivesedation.
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  • Company Name:Hangzhou Yuhao Chemical Technology Co., Ltd
  • Tel:0571-82693216
  • Products Intro:Product Name:Chlordiazepoxide hydrochloride
    CAS:438-41-5
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  • CB Index:52
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  • Company Name:Nanjing Sunlida Biological Technology Co., Ltd.
  • Tel:025-57798810
  • Products Intro:Product Name:CHLORDIAZEPOXIDE HYDROCHLORIDE
    CAS:438-41-5
    Purity:98% Remarks:SLD-3341 More...
  • CB Index:55
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  • Company Name:Raw material medicin reagent co.,Ltd
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  • Products Intro:Product Name:CHLORDIAZEPOXIDE HYDROCHLORIDE
    CAS:438-41-5
    Purity:98% Package:5800RMB/5G More...
  • CB Index:58
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  • Company Name:Zhejiang J&C Biological Technology Co.,Limited
  • Tel:+1-2135480471 +1-2135480471
  • Products Intro:Product Name:Chlordiazepoxide hydrochloride
    CAS:438-41-5
    Purity:99% Package:5KG;1KG Remarks:Chlordiazepoxide hydrochloride
  • CB Index:58
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