Icotinib
610798-31-7 Basic informationMore
- Product Name:Icotinib
- Synonyms: BPI-2009 BP-1096 BPI-2009H Lcotinib Icotinib [1,4,7,10]Tetraoxacyclododecino[2,3-g]quinazolin-4-amine, N-(3-ethynylphenyl)-7,8,10,11,13,14-hexahydro- Icotinib int. N-1 N-(3-Ethynylphenyl)-7,8,10,11,13,14-hexahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]quinazolin
- CAS:610798-31-7
- MF:C22H21N3O4
- MW:391.42
- EINECS:1592732-453-0
- Mol File:610798-31-7.mol
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USE
Icotinib (Conmana?, BetaPharma), an EGFR inhibitor, was approved by the China State FDA in 2011 for the treatment of NSCLC. Icotinib resembles erlotinib in possessing the N-(3-ethylnylphenyl) quinazolin-4-amine core scaffold of erlotinib that binds to the EGFR ATP pocket. An adjacent hydrophobic group was also retained while the solvent exposed two 2-methoxyethyoxysubstituents at the 6- and 7-positions of the quinazoline core were cyclized to afford the tetraoxacyclododecene moiety of icotinib. Efficacy and safety of icotinib as first-line therapy in patients has been evaluated for advanced NSCLC in recent clinical studies.
Lastest Price from Icotinib manufacturers
- Icotinib
-
- US $15.00-10.00/KG
- CAS:610798-31-7
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- 2021-07-13
- Icotinib
-
- US $15.00-10.00/KG
- CAS:610798-31-7
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- 2021-07-10
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- Company Name:Shanghai Aladdin Bio-Chem Technology Co.,LTD
- Tel:400-400-6206333 18521732826
- Products Intro:Product Name:Icotinib
CAS:610798-31-7
Purity:>=99% Package:10mg/RMB 2224.90;50mg/RMB 6488.90;5mg/RMB 1390.90 More... - CB Index:65
- Related Information:Catalog(25003)
- Company Name:Guangzhou Isun Pharmaceutical Co., Ltd
- Tel:020-39119399 18927568969
- Products Intro:Product Name:Icotinib
CAS:610798-31-7
Purity:98% Package:1G; 5G; 25G; 100G; 1KG; 5KG - CB Index:55
- Related Information:Catalog(4674)
- Company Name:Finetech Industry Limited
- Tel:027-87465837 19945049750
- Products Intro:Product Name:Icotinib
CAS:610798-31-7
Purity:98% Package:1g,10g,25g,100g,500g,1kg - CB Index:58
- Related Information:Catalog(9648)
- Company Name:Hunan HuaTeng Pharmaceutical Co., Ltd.,
- Tel: 400-8592883 15367835770
- Products Intro:Product Name:Icotinib
CAS:610798-31-7
Purity:0.98 Package:1g;25g;100g;500g;1kg;25kg More... - CB Index:58
- Related Information:Catalog(5873)