IWR-1-endo
1127442-82-3 Basic informationMore
- Product Name:IWR-1-endo
- Synonyms: [(3aR*,4S*,7R*,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide Benzamide, 4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinyl-, rel- endo-IWR 1 IWR-1-endo rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-Methano-2H-isoindol-2-yl]-N-8-quinolinylbenzaMide rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide IWR-1-endo IWR-1-endo, >=98% ENDO-IWR 1;IWR-1-ENDO;IWR1;IWR 1
- CAS:1127442-82-3
- MF:C25H19N3O3
- MW:409.44
- EINECS:
- Mol File:1127442-82-3.mol
-
USE
<p>IWR-1-endo act as inhibitors of Wnt response. It appear that IWR compounds induce stabilization of Axin proteins via a direct interaction, which is a part of the b-catenin destruction complex (consists of Apc, Axin, Ck1 and Gsk3b). Such compounds may be used in the treatment of Wnt protein signaling-related diseases and conditions such as cancer, degenerative diseases, type II diabetes and osteopetrosi s.</p>
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:IWR-1
CAS:1127442-82-3
Package:100Mg,10Mg More... - CB Index:76
- Related Information:Catalog(96815)
- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:endo-IWR 1;[(3aR*,4S*,7R*,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-Methano-2H-isoindol-2-yl]-N-8-quinolinylbenzaMide
CAS:1127442-82-3
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
- Related Information:Catalog(15839)
- Company Name:Dalian Meilun Biotech Co., Ltd.
- Tel:0411-62910999 13889544652
- Products Intro:Product Name:IWR-1-endo
CAS:1127442-82-3
Purity:>98%,Wnt Package:10MG More... - CB Index:58
- Related Information:Catalog(4727)
- Company Name:Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
- Tel:025-66099280 17798518460
- Products Intro:Product Name:IWR-1-Endo
CAS:1127442-82-3
Purity:95% Package:1g;5g;10g More... - CB Index:55
- Related Information:Catalog(19915)