Muromonab-CD3
140608-64-6 Basic informationMore
- Product Name:Muromonab-CD3
- Synonyms: Muromonab-CD3 Muromonab-CD3 USP/EP/BP Research Grade Muromonab(DHC27701) Research Grade Muromonab-Cd3 Research Grade Muromonab Muromonab (anti-CD3)
- CAS:140608-64-6
- MF:
- MW:0
- EINECS:
- Mol File:Mol File
USE
Muromonab-CD3 (murine, Orthoclone-OKT3) is an unmodified mouse immunoglobulin, an IgG2a, monoclonal. It binds a glycoprotein on the surface of mature T lymphocytes. Mature T cells have, as part of the signal transduction machinery of the T-cell receptor complex, a set of three glycoproteins that are collectively called CD3. Together with the protein zeta, the CD3 molecules become phosphorylated when the T-cell receptor is bound to a peptide fragment and the major histocompatibility complex. The phosphorylated CD3 and zeta molecules transmit information into the cell, ultimately producing transcription factors that enter the nucleus and direct the T-cell activity. By binding to CD3, muromonab-CD3 prevents signal transduction into T cells.<br/>Muromonab-CD3 blocks the function of T cells thatare involved in acute renal rejection. Hence, it is indicatedfor the treatment of acute allograft rejection in heart andliver transplant recipients resistant to standard steroidtherapies.
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- Company Name:Dideu Industries Group Limited
- Tel:+86-29-89586680 +86-15129568250
- Products Intro:Product Name:Muromonab-CD3
CAS:140608-64-6
Purity:99.9% Package:1g;1.1USD Remarks:FDA GMP CEP Approved Manufacturer - CB Index:58
- Related Information:Catalog(29474)
- Company Name:Wuhan Chemstan Biotechnology Co., Ltd.
- Tel: 15926423062
- Products Intro:Product Name:Muromonab-Cd3
Purity:>95%;1mg/ml Package:200ug;500ug;1mg - CB Index:58
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- Company Name:AntibodySystem
- Tel:027-65279366 18162686757
- Products Intro:Product Name:Research Grade Muromonab(DHC27701)
CAS:140608-64-6
Purity:PAGE:>95% Package:100ug;1mg - CB Index:58
- Related Information:Catalog(9784)
- Company Name:Wuhan Jingkangen Biomedical Technology Co., Ltd
- Tel:13720134139 13720134139
- Products Intro:Product Name:Muromonab-Cd3
CAS:140608-64-6
Purity:95% Package:100ug:500ug:1mg - CB Index:58
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- Company Name:Shanghai Aladdin Biochemical Technology Co.,Ltd.
- Tel: +86-18521732826
- Products Intro:Product Name:Muromonab (anti-CD3)
CAS:140608-64-6
Purity:Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Mouse IgG2a; CHO; ELISA, FA Package:10mg/RMB 13699.90;1mg/RMB 3399.90;5mg/RMB 8499.90 - CB Index:58
- Related Information:Catalog(46692)
- Company Name:Shanghai jerryxing Biomedical Technology Co., Ltd
- Tel: 17721492509
- Products Intro:Product Name:Research Grade Muromonab
CAS:140608-64-6
- CB Index:58
- Related Information:Catalog(5347)