Muromonab-CD3
140608-64-6 Basic informationMore
- Product Name:Muromonab-CD3
- Synonyms: Muromonab-CD3 Muromonab-CD3 USP/EP/BP Research Grade Muromonab(DHC27701) Research Grade Muromonab-Cd3 Research Grade Muromonab Muromonab (anti-CD3) Muromonab
- CAS:140608-64-6
- MF:
- MW:0
- EINECS:
- Mol File:Mol File
USE
Muromonab-CD3 (murine, Orthoclone-OKT3) is an unmodified mouse immunoglobulin, an IgG2a, monoclonal. It binds a glycoprotein on the surface of mature T lymphocytes. Mature T cells have, as part of the signal transduction machinery of the T-cell receptor complex, a set of three glycoproteins that are collectively called CD3. Together with the protein zeta, the CD3 molecules become phosphorylated when the T-cell receptor is bound to a peptide fragment and the major histocompatibility complex. The phosphorylated CD3 and zeta molecules transmit information into the cell, ultimately producing transcription factors that enter the nucleus and direct the T-cell activity. By binding to CD3, muromonab-CD3 prevents signal transduction into T cells.<br/>Muromonab-CD3 blocks the function of T cells thatare involved in acute renal rejection. Hence, it is indicatedfor the treatment of acute allograft rejection in heart andliver transplant recipients resistant to standard steroidtherapies.
Lastest Price from Muromonab-CD3 manufacturers
Browse by Nationality 140608-64-6 Suppliers >Global suppliers
Beijing (1) Shanghai (5) Guangdong (1) Zhejiang (1) Hunan (1) Hubei (3) Shaanxi (1) Member (13) All (13)
Please select the suppliers
Recommend You Select Member Companies
Recommend You Select Member Companies
- Company Name:Dideu Industries Group Limited
- Tel:+86-29-89586680 +86-15129568250
- Products Intro:Product Name:Muromonab-CD3
CAS:140608-64-6
Purity:99.9% Package:1g;1.1USD Remarks:FDA GMP CEP Approved Manufacturer - CB Index:58
- Related Information:Catalog(22787)
- Company Name:Guangzhou Hongyuan Chemical Co.,Ltd
- Tel: 15817493340
- Products Intro:Product Name:Muromonab
CAS:140608-64-6
Purity:95% Package:1mg;1g;100g - CB Index:58
- Related Information:Catalog(1566)
- Company Name:Wuhan Chemstan Biotechnology Co., Ltd.
- Tel:027-65317797 15926423062
- Products Intro:Product Name:Muromonab-Cd3
Purity:>95%;1mg/ml Package:200ug;500ug;1mg - CB Index:58
- Related Information:Catalog(10436)
- Company Name:Biolab Reagents
- Tel:027-65279366 18108604862
- Products Intro:Product Name:Research Grade Muromonab(DHC27701)
CAS:140608-64-6
Purity:PAGE:>95% Package:100ug;1mg - CB Index:58
- Related Information:Catalog(9818)
- Company Name:Wuhan Jingkangen Biomedical Technology Co., Ltd
- Tel:13720134139 13720134139
- Products Intro:Product Name:Muromonab-Cd3
CAS:140608-64-6
Purity:95% Package:100ug:500ug:1mg - CB Index:58
- Related Information:Catalog(5821)
- Company Name:Shanghai Yifei Biotechnology Co. , Ltd.
- Tel:021-65675885 18964387627
- Products Intro:Product Name:Muromonab
CAS:140608-64-6
Purity:95% Package:1mg;5mg;10mg - CB Index:58
- Related Information:Catalog(11974)