AG 490
134036-52-5 Basic informationMore
- Product Name:AG 490
- Synonyms: AG 490, Tryphostin B42 2-Cyano-3-(3,4-dihydroxyphenyl)-N-benzylacrylamide N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)propenamide TYROPHOSTIN AG490 TYRPHOSTIN B42 TYRPHOSTIN AG 490, 99+% N-Benzyl-2-(3,4-dihydroxybenzylidene)-2-cyanoacetamide (E)-2-CYANO-3-(3,4-DIHYDROPHENYL)-N-(PHENYLMETHYL)-2-PROPENAMIDE
- CAS:134036-52-5
- MF:C17H14N2O3
- MW:294.31
- EINECS:604-604-1
- Mol File:134036-52-5.mol
-
USE
A potent and specific inhibitor of the Jak-2 tyrosine kinase. In acute lymphoblastic leukemia (ALL) cells which abundantly express JAK-2, AG-490 dose-dependently inhibited DNA synthesis, blocked cell growth and induced apoptosis. AG-490 does not significantly inhibit other kinases such as Lck, Lyn, Btk, Syk and Src. AG-490 is cell permeable and is active in vivo.
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- Company Name:Shanghai Boyle Chemical Co., Ltd.
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- Products Intro:Product Name:AG-490
CAS:134036-52-5
Purity:98%min More... - CB Index:55
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:18210857532 18210857532
- Products Intro:Product Name:AG-490
CAS:134036-52-5
Package:250Mg,25Mg More... - CB Index:76
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- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel: 18930552037
- Products Intro:Product Name:AG 490
CAS:134036-52-5
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
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- Company Name:Chemsky（shanghai）International Co.,Ltd.
- Tel:021-50135380
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CAS:134036-52-5
Purity:98% More... - CB Index:50
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- Company Name:Guangzhou Isun Pharmaceutical Co., Ltd
- Tel:020-39119399 18927568969
- Products Intro:Product Name:AG-490
CAS:134036-52-5
Purity:98.0% Package:50Mg;100Mg;500Mg;1g;5g;10g More... - CB Index:55
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- Company Name:TargetMol Chemicals Inc.
- Tel:021-021-33632979 15002134094
- Products Intro:Product Name:(E/Z)-AG490
CAS:134036-52-5
Package:200mg/RMB 12700 - CB Index:58
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- Company Name:GIHI CHEMICALS CO.,LTD
- Tel:0086-571-86217390
- Products Intro:Product Name:AG-490
CAS:134036-52-5
Purity:98% HPLC Package:5g/bag;100g/bag;1kg/bag;5kg/bag;25kg/bag More... - CB Index:58
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- Company Name:Bide Pharmatech Ltd.
- Tel:400-164-7117 18317119277
- Products Intro:Product Name:N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide
CAS:134036-52-5
Purity:98% Package:10mg;50mg;100mg;250mg;1g Remarks:BD16592 - CB Index:60
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