AG 490
134036-52-5 Basic informationMore
- Product Name:AG 490
- Synonyms: AG 490, Tryphostin B42 2-Cyano-3-(3,4-dihydroxyphenyl)-N-benzylacrylamide N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)propenamide TYRPHOSTIN AG 490 TYROPHOSTIN AG490 TYRPHOSTIN B42 TYRPHOSTIN AG 490, 99+% N-Benzyl-2-(3,4-dihydroxybenzylidene)-2-cyanoacetamide
- CAS:134036-52-5
- MF:C17H14N2O3
- MW:294.3
- EINECS:604-604-1
- Mol File:134036-52-5.mol
-
USE
A potent and specific inhibitor of the Jak-2 tyrosine kinase. In acute lymphoblastic leukemia (ALL) cells which abundantly express JAK-2, AG-490 dose-dependently inhibited DNA synthesis, blocked cell growth and induced apoptosis. AG-490 does not significantly inhibit other kinases such as Lck, Lyn, Btk, Syk and Src. AG-490 is cell permeable and is active in vivo.
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:AG-490
CAS:134036-52-5
Package:250Mg,25Mg More... - CB Index:76
- Related Information:Catalog(96815)
- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:AG 490
CAS:134036-52-5
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
- Related Information:Catalog(15839)
- Company Name:Guangzhou Isun Pharmaceutical Co., Ltd
- Tel:020-39119399 18927568969
- Products Intro:Product Name:AG-490
CAS:134036-52-5
Purity:98.0% Package:50Mg;100Mg;500Mg;1g;5g;10g More... - CB Index:55
- Related Information:Catalog(4428)
- Company Name:TargetMol Chemicals Inc.
- Tel:021-021-33632979 15002134094
- Products Intro:Product Name:(E/Z)-AG490
CAS:134036-52-5
Package:200mg/RMB 12700 - CB Index:58
- Related Information:Catalog(7783)