Almotriptan
154323-57-6 Basic informationMore
- Product Name:Almotriptan
- Synonyms: LAS-31416-d6 ALMOTRIPTAN(SUBJECTTOPATENETFREE) Almotriptan N,N-Dimethyl-2-[5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indol-3-yl]-ethanamine dimethyl-[2-[5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indol-3-yl]ethyl]amine AlMotriptan API N,N-dimethyl-5-[(1-pyrrolidinylsulfonyl)methyl]-1H-Indole-3-ethanamine ALMOTRIPTAN-D6
- CAS:154323-57-6
- MF:C17H25N3O2S
- MW:335.46
- EINECS:1312995-182-4
- Mol File:154323-57-6.mol
-
USE
Almotriptan was first marketed in Spain as a new medicine against acute attacks of migraine. It is the fifth agent belonging to the “triptan” class to be launched after sumatriptan, naratriptan, zolmitriptan and rizatriptan. Almotriptan acts as a dual 5-HT1D/1B agonist with a 35 to 51-fold selectivity versus 5-HT1A and 5-HT7 receptors respectively as well as having insignificant affinity for the most relevant nonserotonergic receptors (K1＞1μM). Its agonistic effect on 5-HT,n receptors of trigeminal sensory neurons turns off neurogenic inflammation by inhibiting the release of neuropeptides such as calcitonin gene-related peptide, neurokinin A and substance P.
Lastest Price from Almotriptan manufacturers
Browse by Nationality 154323-57-6 Suppliers >Global suppliers
Beijing (4) Shanghai (21) Tianjin (1) Chongqing (2) Sichuan (1) Guangdong (2) Zhejiang (4) Fujian (3) Hubei (10) Shandong (3) Henan (3) Anhui (2) Jiangsu (18) Jiangxi (2) Shaanxi (3) Hong Kong (1) Taiwan (1) Other (1) Member (74) All (82)
Please select the suppliers
Recommend You Select Member Companies
Recommend You Select Member Companies
- Company Name:Nanjing Chemlin Chemical Co., Ltd
- Tel:025-83697070
- Products Intro:Product Name:Almotriptan
CAS:154323-57-6
Purity:98% Package:5KG; 1KG More... - CB Index:64
- Related Information:Catalog(19179)
- Company Name:Beijing Yisiyan Technology Research Center
- Tel:010-56645598 13366904824
- Products Intro:Product Name:N,N-diMethyl-2-[5-(pyrrolidin-1-ylsulfonylMethyl)-1H-indol-3-yl]EthanaMine
CAS:154323-57-6
Purity:>98% Package:10g;50g;500g More... - CB Index:59
- Related Information:Catalog(1638)
- Company Name:Shanghai Worldyang Chemical Co.,Ltd.
- Tel:021-021-56795766
- Products Intro:Product Name:AlMotriptan
CAS:154323-57-6
Purity:97% Package:100g;1kg More... - CB Index:58
- Related Information:Catalog(9346)
- Company Name:ChemStrong Scientific Co.,Ltd
- Tel:0755-0755-66853366 13670046396
- Products Intro:Product Name:Almotriptan
CAS:154323-57-6
Purity:95% HPLC Package:10mg;25mg;50mg;100mg - CB Index:56
- Related Information:Catalog(18070)
- Company Name:Mashilabs (Shanghai) Co.,Ltd.
- Tel: 19916721580
- Products Intro:Product Name:Almotriptan
CAS:154323-57-6
Purity:0.98 - CB Index:58
- Related Information:Catalog(4296)