Almotriptan
154323-57-6 Basic informationMore
- Product Name:Almotriptan
- Synonyms: LAS-31416-d6 ALMOTRIPTAN(SUBJECTTOPATENETFREE) Almotriptan N,N-Dimethyl-2-[5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indol-3-yl]-ethanamine dimethyl-[2-[5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indol-3-yl]ethyl]amine AlMotriptan API N,N-dimethyl-5-[(1-pyrrolidinylsulfonyl)methyl]-1H-Indole-3-ethanamine ALMOTRIPTAN-D6
- CAS:154323-57-6
- MF:C17H25N3O2S
- MW:335.46
- EINECS:1312995-182-4
- Mol File:154323-57-6.mol
-
USE
Almotriptan was first marketed in Spain as a new medicine against acute attacks of migraine. It is the fifth agent belonging to the “triptan” class to be launched after sumatriptan, naratriptan, zolmitriptan and rizatriptan. Almotriptan acts as a dual 5-HT1D/1B agonist with a 35 to 51-fold selectivity versus 5-HT1A and 5-HT7 receptors respectively as well as having insignificant affinity for the most relevant nonserotonergic receptors (K1＞1μM). Its agonistic effect on 5-HT,n receptors of trigeminal sensory neurons turns off neurogenic inflammation by inhibiting the release of neuropeptides such as calcitonin gene-related peptide, neurokinin A and substance P.
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- Company Name:Nanjing Chemlin Chemical Co., Ltd
- Tel:025-83697070
- Products Intro:Product Name:Almotriptan
CAS:154323-57-6
Purity:98% Package:5KG; 1KG More... - CB Index:64
- Related Information:Catalog(19172)
- Company Name:Beijing Yisiyan Technology Research Center
- Tel:010-56645598 13366904824
- Products Intro:Product Name:N,N-diMethyl-2-[5-(pyrrolidin-1-ylsulfonylMethyl)-1H-indol-3-yl]EthanaMine
CAS:154323-57-6
Purity:>98% Package:10g;50g;500g More... - CB Index:59
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- Company Name:Shanghai Worldyang Chemical Co.,Ltd.
- Tel:021-021-56795766
- Products Intro:Product Name:AlMotriptan
CAS:154323-57-6
Purity:97% Package:100g;1kg More... - CB Index:58
- Related Information:Catalog(9346)
- Company Name:ChemStrong Scientific Co.,Ltd
- Tel:0755-0755-66853366 13670046396
- Products Intro:Product Name:Almotriptan
CAS:154323-57-6
Purity:95% HPLC Package:10mg;25mg;50mg;100mg - CB Index:56
- Related Information:Catalog(18042)
- Company Name:Mashilabs (Shanghai) Co.,Ltd.
- Tel: 19916721580
- Products Intro:Product Name:Almotriptan
CAS:154323-57-6
Purity:0.98 - CB Index:58
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