Clioquinol
130-26-7 Basic informationMore
- Product Name:Clioquinol
- Synonyms: 5-chloro-7-iodo-8-quinolino 7-Iodo-5-chloroxine 8-Quinolinol, 5-chloro-7-iodo- ala-quin Alchloquin alchoquin alioform Amebil
- CAS:130-26-7
- MF:C9H5ClINO
- MW:305.5
- EINECS:204-984-4
- Mol File:130-26-7.mol
USE
Clioquinol, a halogenated hydroxyquinoline derivative, was
introduced into medicine around 1900 as a topical antiseptic and in 1934 oral
preparations for the treatment of amoebic dysentery and simple diarrhoea became
available. By 1964 its use in Japan had been associated with cases of sub-acute
myelo-optic neuropathy (SMON) which reached epidemic proportions resulting in
its withdrawal there in 1970. Although relatively few cases of SMON were
documented elsewhere, clioquinol was subsequently withdrawn from use in many
countries and placed under prescription control in others. It was phased out
worldwide by the major manufacturer between 1983 and 1985 on grounds of
obsolescence. No adequately controlled evidence was ever generated to
demonstrate that clioquinol is effective in bacterial or viral diarrhoea. However,
products containing clioquinol and related halogenated hydroxyquinolines
continue to be used in some tropical and subtropical countries where amoebiasis
remains endemic. Other amoebocides are preferred in the WHO Model List of
Essential Drugs.
(Reference: (WHODI) WHO Drug Information, 77.1, 9, 1977)
Lastest Price from Clioquinol manufacturers
- Clioquinol
- US $0.00-0.00/Kg/Drum
- CAS:130-26-7
- Min. Order: 1KG
- Purity: I: 38%-42% Cl: 11%-12.4%
- Supply Ability: 100KGS
- 2024-11-21
- Clioquinol
- US $50.00 /kg
- CAS:130-26-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1000tons
- 2023-09-07
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- Company Name:Tianjin Tianyao Pharmaceuticals Co., Ltd
- Tel:22-24160838
- Products Intro:CAS:130-26-7
More... - CB Index:60
- Related Information:Catalog(64)
- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:5-Chloro-8-hydroxy-7-iodoquinoline
CAS:130-26-7
Purity:98.0%(T) Package:250G,25G More... - CB Index:76
- Related Information:Catalog(94657)
- Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel:021-61259108 18621169109
- Products Intro:Product Name:5-Chloro-8-hydroxy-7-iodoquinoline
CAS:130-26-7
Purity:>98.0%(T) Package:25g;250g Remarks:C0187 More... - CB Index:62
- Related Information:Catalog(40228)
- Company Name:TCI (Shanghai) Development Co., Ltd.
- Tel:021-67121386
- Products Intro:Product Name:5-Chloro-8-hydroxy-7-iodoquinoline
CAS:130-26-7
Purity:97.0% T Package:250G,25G More... - CB Index:81
- Related Information:Catalog(24529)
- Company Name:Energy Chemical
- Tel:021-021-58432009 400-005-6266
- Products Intro:Product Name:Clioquinol
CAS:130-26-7
Purity:98% Package:10g,250g,50g More... - CB Index:61
- Related Information:Catalog(44689)