Cabozantinib
849217-68-1 Basic informationMore
- Product Name:Cabozantinib
- Synonyms: Cabozantinib(XL184Malate) Cabozantinib (XL184, BMS-907351) XL-186 1,1-cyclopropanedicarboxamide, n'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n-(4-fluorophenyl)- N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide Cabozantinib (XL184, BMS-907351) Cabozantinib, >=98% 1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide N-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide Cabozantinib
- CAS:849217-68-1
- MF:C28H24FN3O5
- MW:501.51
- EINECS:692-846-8
- Mol File:849217-68-1.mol
USE
In clinical trials, common adverse effects caused by cabozantinib include diarrhea, stomatitis, palmar-plantarrythrodysesthesia syndrome (PPES), and loss of weight, loss of appetite, nausea, fatigue, oral pain, taste disorders, high blood pressure, abdominal pain and constipation.<br />
The most common laboratory abnormalities (> 25%) were increased aspartate aminotransferase, alanine aminotransferase, lymphopenia, increased alkaline phosphatase level, hypocalcemia, neutropenia, thrombocytopenia, hypophosphatemia and hyperbilirubinemia.<br />
For patients receiving cabozantinib, 57% of patients have gotten increased level of thyroid stimulating hormone after initial dose, compared with patients receiving placebo, increased by 19%.<br />
Information regarding to the anticancer drug, mechanism of action, pharmacokinetics, side effects, and drug interactions of cabozantinib were compiled and edited by Yan Shi from Chemicalbook. (2015-10-23)
Lastest Price from Cabozantinib manufacturers
- Cabozantinib
- US $0.00-0.00/g
- CAS:849217-68-1
- Min. Order: 10g
- Purity: 99%
- Supply Ability: 10000
- 2024-12-17
- Cabozantinib
- US $0.00 /g
- CAS:849217-68-1
- Min. Order: 1g
- Purity: 99%min
- Supply Ability: 1000g
- 2024-12-13
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- Company Name:Shandong Haiwo Biological Technology Co., Ltd.
- Tel:0531-87586188 13046003282
- Products Intro:Product Name:Cabozantinib
CAS:849217-68-1
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- Company Name:Henan Puhui Tiancheng Biotechnology Co., Ltd
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