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Procainamide hydrochloride

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USE
Procainamide hydrochloride is metabolized through theaction of N-acetyltransferase. The product of enzymaticmetabolism of procainamide hydrochloride is N-acetylprocainamide(NAPA), which possesses only 25% of the activityof the parent compound.26 A study of the disposition ofprocainamide hydrochloride showed that 50% of the drugwas excreted unchanged in the urine, with 7% to 24% recoveredas NAPA.28,29 Unlike quinidine, procainamide hydrochlorideis bound only minimally to plasma proteins.Between 75% and 95% of the drug is absorbed from the gastrointestinaltract. Plasma levels appear 20 to 30 minutesafter administration and peak in about 1 hour.30Procainamide hydrochloride appears to have all of theelectrophysiological effects of quinidine. It diminishesautomaticity, decreases conduction velocity, and increasesaction potential duration and, thereby, the refractory periodof myocardial tissue. Clinicians have favored the use of procainamidehydrochloride for ventricular tachycardias andquinidine for atrial arrhythmias, even though the two drugsare effective in either type of disorder.
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  • Company Name:Chongqing Botao Biotechnology Co., LTD
  • Tel:15223382610 15223382610
  • Products Intro:Product Name:Procainamide hydrochloride
    CAS:614-39-1
    Purity:99% Package:25kg;5KG;1KG
  • CB Index:58
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  • Company Name:Shaanxi kelkai Pharmaceutical Technology Co., Ltd
  • Tel:029-029-2148545164 17392779578
  • Products Intro:Product Name:Procainamide hydrochloride
    CAS:614-39-1
    Purity:99% HPLC Package:5KG;1KG
  • CB Index:58
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  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:010-82848833 400-666-7788
  • Products Intro:Product Name:Procainamide hydrochloride, 99%
    CAS:614-39-1
    Purity:99% Package:100G;25G More...
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  • Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
  • Tel:021-61259108 18621169109
  • Products Intro:Product Name:ProcainaMide hydrochloride
    CAS:614-39-1
    Purity:99% Remarks:20730 More...
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  • Company Name:Chembest Research Laboratories Limited
  • Tel:+86-21-20908456
  • Products Intro:Product Name:ProcainaMide hydrochloride
    CAS:614-39-1
    Remarks:C14057 More...
  • CB Index:61
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  • Company Name:Beijing Ouhe Technology Co., Ltd
  • Tel:010-82967028 13552068683
  • Products Intro:Product Name:Procainamide hydrochloride
    CAS:614-39-1
    Purity:98% Package:10g;50g;100g;250g;500g More...
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