Necrostatin-1
4311-88-0 Basic informationMore
- Product Name:Necrostatin-1
- Synonyms: Necrostatin-1, >=98% IFLAB-BB F0911-6127 5-(INDOL-3-YLMETHYL)-3-METHYL-2-THIO-HYDANTOIN NECROSTATIN-1 MTH-DL-TRYPTOPHAN MTH-DL-Tryptophan Methylthiohydantoin-DL-tryptophan 5-(1H-INDOL-3-YLMETHYL)-3-METHYL-2-THIOXO-4-IMIDAZOLIDINONE 5-(1H-Indole-3ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone
- CAS:4311-88-0
- MF:C13H13N3OS
- MW:259.33
- EINECS:200-256-5
- Mol File:4311-88-0.mol
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USE
Necrostatin-1 (1-100 μM) inhibits the autophosphorylation of overexpressed and endogenous RIP1.It is found RIP1 is the primary cellular target responsible for the antinecroptosis activity of Necrostatin-1. Necrostatin-1 efficiently suppresses necroptotic cell death triggered by an array of stimuli in a variety of cell types. Necrostatin-1, previously identified as small-molecule inhibitor of necroptosis, inhibits RIP kinase-induced necroptosis and inhibits TNF-α-induced necroptosis in jurkat cells with EC50 of 490 nM.
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- Company Name:Tianjin Kailiqi Biotechnology Co., Ltd.
- Tel: 15076683720
- Products Intro:Product Name:Necrostatin-1
CAS:4311-88-0
Purity:>98% Package:2g Remarks:2g More... - CB Index:55
- Related Information:Catalog(4597)
- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:Necrostatin-1, 98%
CAS:4311-88-0
Purity:98% Package:100MG;10MG;50MG More... - CB Index:76
- Related Information:Catalog(96815)
- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:Necrostatin-1;5-(1H-Indol-3-ylMethyl)-3-Methyl-2-thioxo-4-iMidazolidinone
CAS:4311-88-0
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
- Related Information:Catalog(15839)
- Company Name:Shanghai Hanhong Scientific Co.,Ltd.
- Tel:021-54306202 13764082696
- Products Intro:Product Name:Necrostatin-1
CAS:4311-88-0
Purity:98+% Remarks:AB10670 More... - CB Index:64
- Related Information:Catalog(42958)