Basic information Supplier

119141-88-7

Basic information Supplier
119141-88-7 Basic informationMore
USE
Esomeprazole, formulated as a magnesium salt, reached the market as a treatment for acid-related diseases such as gastro-esophageal reflux (GERD) disease including peptic ulcer disease and reflux esophagitis. Esomeprazole (formerly perprazole) is the active (S)- enantiomer of omeprazole (1988) and the first proton pump inhibitor developed as an optical isomer. It can be obtained by several routes such as asymmetric oxidation of the pro-chiral pyridylmethyl benzimidazole sulfide, separation from the racemic sulfoxide by chiral chromatography or separation of a diastereomeric mixture obtained from the racemic compound and a chiral acid, followed by hydrolysis. Biochemical studies have shown that esomeprazole irreversibly inhibits the gastric H<sup>+</sup>/K<sup>+</sup>-adenosine triphosphatase (ATPase), an enzyme system involved at the secretory surface of the stomach’s parietal cells responsible for the secretion of gastric acid. Compared with racemic omeprazole in healthy subjects, esomeprazole has higher bioavailability, is absorbed more rapidly and exhibits a more uniform and predictable dose-response with higher plasma levels, leading to less inter-individual variability between slow and rapid metabolizers. In extensive clinical trials in patients suffering from GERD symptoms, esomeprazole provided superior acid control and significantly reduced the healing time compared to omeprazole.
Lastest Price from Esomeprazole manufacturers
  • Esomeprazole
  • US $1.00-1.00/KG
  • CAS:119141-88-7
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 50tons
  • 2020-05-12

Browse by Nationality 119141-88-7 Suppliers >Global suppliers

Beijing (7) Shanghai (27) Chongqing (5) Sichuan (2) Guangdong (11) Zhejiang (14) Fujian (1) Hunan (1) Hubei (32) Shandong (10) Henan (5) Hebei (1) Anhui (3) Jiangsu (20) Shaanxi (4) Other (2) Member (128) All (145)
Please select the suppliers
Recommend You Select Member Companies
  • Company Name:Chembest Research Laboratories Limited
  • Tel:021-20908456-
  • Products Intro:Product Name:EsoMeprazole
    CAS:119141-88-7
    Remarks:C13642 More...
  • CB Index:61
  • Related Information:Catalog(5953)
  •  
  • Company Name:Hangzhou Luckysage Sciene and Technology Co.,Ltd
  • Tel:0571-88199336
  • Products Intro:Product Name:Esomeprazole
    CAS:119141-88-7
    Purity:99% HPLC Package:5KG;1KG More...
  • CB Index:64
  • Related Information:Catalog(60)
  •  
  • Company Name:Nanjing Chemlin Chemical Co., Ltd
  • Tel:025-83697070-
  • Products Intro:CAS:119141-88-7
    Purity:97% Package:10g;500g;1kg;10kg More...
  • CB Index:64
  • Related Information:Catalog(19994)
  •  
  • Company Name:Shanghai Hanhong Scientific Co.,Ltd.
  • Tel:021-54306202-
  • Products Intro:Product Name:Esomeprazole
    CAS:119141-88-7
    Remarks:AB02621 More...
  • CB Index:64
  • Related Information:Catalog(43258)
  •  
  • Company Name:Wuhan Sinocon New chemical Materials Co.,ltd.
  • Tel:13971313286 027-83229541
  • Products Intro:Product Name:Esomeprazole
    Remarks:only for researching, commercial products can NOT be available. More...
  • CB Index:62
  • Related Information:Catalog(127)
  •  
  • Company Name:Hangzhou Yuhao Chemical Technology Co., Ltd
  • Tel:0571-82693216
  • Products Intro:CAS:119141-88-7
    More...
  • CB Index:52
  • Related Information:Catalog(9406)
  •  
  • Company Name:Wuhan Fortuna Chemical Co., Ltd
  • Tel:13308628970 027-59207852-
  • Products Intro:Product Name:Esomeprazole
    CAS:119141-88-7
    Purity:98% Package:5kg/ More...
  • CB Index:58
  • Related Information:Catalog(2984)
  •  
  • Company Name:Acorn PharmaTech Co., Ltd.
  • Tel:025-58395930-
  • Products Intro:Product Name:5-Methoxy-2-(4-Methoxy-3,5-diMethyl-pyridin-2-ylMethanesulfinyl)-1H-benzoiMidazole
    CAS:119141-88-7
    Purity:98% Package:1g,10g,100g,1kg,10kg More...
  • CB Index:60
  • Related Information:Catalog(982)
  •  
1 2 3 4 5 16