APHIDICOLIN
38966-21-1 Basic informationMore
- Product Name:APHIDICOLIN
- Synonyms: (3-ALPHA,4-ALPHA,5-ALPHA,17-ALPHA)-3,17-DIHYDROXY-4-METHYL-9,15-CYCLO-C,18-DINOR-14,15-SECOANDROSTANE-4,17-DIMETHANOL (+)-APHIDICOLIN APHIDICOLIN (+)-APHIDICOLIN, NIGROSPORA ORYZAE ,11a-beta,11b-beta))- 9-dimethanol,tetradecahydro-3,9-11a-methano-11ah-cyclohepta(a)naphthalene-4 dihydroxy-4,11b-dimethyl-,(3r-(3-alpha,4-alpha,4a-alpha,6a-beta,8-beta,9-beta ici69653
- CAS:38966-21-1
- MF:C20H34O4
- MW:338.48
- EINECS:609-602-3
- Mol File:38966-21-1.mol
-
USE
Aphidicolin is a tetracyclic diterpene antibiotic isolated from fungi, notably Cephalosporium, Nigrospora, Harziella and Phoma. Aphidicolin has antibiotic, antiviral and antimitotic properties, blocking the cell cycle at early S-phase. This property has been used to synchronise cell division and is useful as a tool in cell differentiation research. Aphidicolin is a reversible inhibitor of DNA replication by inhibiting selected DNA polymerases. Aphidicolin induces apoptosis, prolongs the half-life of DNA methyltransferase, is active against Leishmania parasites and acts synergistically with the antitumor agents, vincristine and doxorubicin.
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- Company Name:J & K SCIENTIFIC LTD.
- Tel: 18210857532
- Products Intro:Product Name:Aphidicolin, 98%, from Nigrospora oryzae
CAS:38966-21-1
Purity:98% Package:1MG;5MG More... - CB Index:76
- Related Information:Catalog(96815)
- Company Name:Shanghai Aladdin Bio-Chem Technology Co.,LTD
- Tel:400-6206333 13167063860
- Products Intro:Product Name:Aphidicolin
CAS:38966-21-1
Purity:98% Package:10mg/RMB 6385.90;1mg/RMB 1247.90;5mg/RMB 3707.90 More... - CB Index:65
- Related Information:Catalog(25003)
- Company Name:Guangzhou Isun Pharmaceutical Co., Ltd
- Tel:020-39119399 18927568969
- Products Intro:Product Name:Aphidicolin fromNigrospora sphaerica
CAS:38966-21-1
Purity:98% (HPLC) Package:5MG; 25MG; 100MG; 1G More... - CB Index:55
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- Company Name:ShangHai Caerulum Pharma Discovery Co., Ltd.
- Tel:18149758185 18149758185
- Products Intro:Product Name:Aphidicolin
CAS:38966-21-1
Purity:98% Package:1g;10g;100g - CB Index:58
- Related Information:Catalog(3466)
- Company Name:Sigma-Aldrich
- Tel:021-61415566 800-8193336
- Products Intro:Product Name:Aphidicolin
CAS:38966-21-1
Purity:>= 98 % HPLC, powder Package:1mg, 5mg, 10mg Remarks:A0781 More... - CB Index:80
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- Company Name:Zhengzhou Alfachem Co., Ltd.
- Tel:0371-53765687 18937137882
- Products Intro:Product Name:(3R,4R,4aR,6aS,8R,9R,11aS,11bS)-4,9-Bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalene-3,9-diol
CAS:38966-21-1
Purity:0.98 Package:25mg;100mg;250mg;500mg;1g;5g - CB Index:55
- Related Information:Catalog(7954)