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Chlorphenesin carbamate

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Chlorphenesin carbamate,3-(p-chlorophenoxy)-1,2-propanediol 1-carbamate (Maolate),is the p-chloro substituted and 1-carbamate derivativeof the lead compound in the development of this group ofagents, mephenesin. Mephenesin is weakly active and shortlivedbecause of facile metabolism of the primary hydroxylgroup. Carbamylation of this group increases activity. p-Chlorination increases the lipophilicity and seals off thepara position from hydroxylation. Metabolism, still fairlyrapid, involves glucuronidation of the secondary hydroxylgroup. The biological half-life in humans is 3.5 hours.

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  • Products Intro:Product Name:CHLORPHENESIN CARBAMATECHLORPHENESIN CARBAMATE
    CAS:886-74-8
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  • Products Intro:Product Name:chlorphenesin carbamate
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