Alectinib

• Product Name:Alectinib
• Synonyms: AF-802 CH-5424802/RG-7853 Alectinib AF-802,RG-7853 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile Alectinib (CH5424802) CH5424802-alectinib 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile CH5424802 CH5424802, Alectinib, AF802
• CAS:1256580-46-7
• MF:C30H34N4O2
• MW:482.62
• EINECS:821-541-6
• Mol File:1256580-46-7.mol
• 

Alectinib (Alecensa(R), Roche) was approved first in Japan in 2014 and then by US FDA in 2015 as a second-generation ALK inhibitor for NSCLC treatment on patients who have progressed or do not tolerate crizotinib. Developed through a structure-based drug design approach, alectinib is a benzocarbazolone derivative that has shown potent inhibitory activity against ALK (IC50 value of 1.9 nM) and gatekeeper mutant L1196M ALK (IC50 value of 1.6 nM). Alectinib is effective with crizotinib-resistant ALK mutations on L1196M, F1174L, R1275Q, and C1156Y. In addition, an array of small-molecule inhibitors are currently being evaluated by several clinical trials for ALK-driven tumors.

• Alectinib
• 
• US $0.00 /Kg/Bag
• CAS:1256580-46-7
• Min. Order: 1KG
• Purity: 99%min
• Supply Ability: 500kgs
• 2024-11-22

• Alectinib
• 
• US $0.00-0.00/kg
• CAS:1256580-46-7
• Min. Order: 1kg
• Purity: 99%，single impurity＜0.1
• Supply Ability: 1 ton
• 2024-11-22

• Company Name:Chengdu aibike Pharmaceutical Technology Co., Ltd
• Tel: 18428121256
• Products Intro:Product Name:Alectinib
  CAS:1256580-46-7
  Purity:0.99 Package:5kg Remarks:10kg
• CB Index:58
• Related Information:Catalog(21)

• Company Name:Shanghai Famo Bio-chemical Technology Company Ltd.
• Tel:021-021-36680027 15800370750
• Products Intro:Product Name:Alectinib
  CAS:1256580-46-7
  Purity:98% More...
• CB Index:56
• Related Information:Catalog(540)

• Company Name:Hubei Hicks Biochemical Co., Ltd
• Tel:17362916295; 17362916295
• Products Intro:CAS:1256580-46-7
  Purity:99% HPLC Package:5KG;1KG Remarks:KG
• CB Index:58
• Related Information:Catalog(4046)

• Company Name:NANJING ZENJI PHARMACEUTICALS
• Tel:025-58231105-8151 15190133791;
• Products Intro:Product Name:Alectinib
  CAS:1256580-46-7
  Purity:99% Package:1g;10g;100g;1kg
• CB Index:58
• Related Information:Catalog(441)

• Company Name:Nanjing Becas pharmatech Ltd.
• Tel: 13912903754
• Products Intro:Product Name:Alectinib
  CAS:1256580-46-7
  Purity:97% HPLC Package:1g,5g,10g,25g
• CB Index:58
• Related Information:Catalog(2391)

• Company Name:J & K SCIENTIFIC LTD.
• Tel:010-82848833 400-666-7788
• Products Intro:Product Name:CH5424802
  CAS:1256580-46-7
  Package:100Mg,10Mg,50Mg,5Mg More...
• CB Index:76
• Related Information:Catalog(96815)