Captopril

• Product Name:Captopril
• Synonyms: Captopril (200 mg) Captopril Cardiovascular (S)-(-)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline (S)-(-)-1-(3-Mercapto-2-methylpropionyl)-L-proline 3-Mercapto-2-Methylpropanoic acid 1,2-diphenylethylaMine salt (MMPA) CAPTOPRIL(RG) Captopril (Capoten) (S)-1-((S)-3-mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylic acid Captopril for system suitability
• CAS:62571-86-2
• MF:C9H15NO3S
• MW:217.29
• EINECS:263-607-1
• Mol File:62571-86-2.mol
• 

Captopril, 1-[(2S)-3-mercapto-2-methyl-1-oxopropionyl]proline (Capoten), blocks the conversion of angiotensinI to angiotensin II by inhibiting the convertingenzyme. The rational development of captopril as an inhibitorof ACE was based on the hypothesis that ACE and carboxypeptidaseA functioned by similar mechanisms. It wasnoted that d-2-benzylsuccinic acid was a potent inhibitor ofcarboxypeptidase A, but not ACE. By use of this small molecule as a prototype, captopril was designed with a carboxylgroup on a proline and a thiol group was introduced toenhance the binding to the zinc ion of ACE. The importantbinding points at the active site of ACE are thought to be anarginine residue, which provides a cationic site that attracts acarboxylate ion, and a zinc ion, which can polarize a carbonylgroup of an amide function to make it more susceptible to hydrolysis.Hydrophobic pockets lie between these groups in theactive site, as does a functional group that forms a hydrogenbond with an amide carbonyl.

• Captopril
• 
• US $35.00-1.20/kg
• CAS:62571-86-2
• Min. Order: 1kg
• Purity: 99%
• Supply Ability: g-kg-tons, free sample is available
• 2024-04-18

• Captopril
• 
• US $0.00-0.00/kg
• CAS:62571-86-2
• Min. Order: 1kg
• Purity: 99
• Supply Ability: 10 mt
• 2024-03-15

• Company Name:Lingyuan Bebiansen Biological Technology Co., Ltd
• Tel: 18642120371
• Products Intro:Product Name:Captopril
  CAS:62571-86-2
  Purity:98% Package:5g
• CB Index:58
• Related Information:Catalog(9925)

• Company Name:wuhan dingxingtong Chemical Technology Co., Ltd Co., Ltd
• Tel:027-59207796 13429867250
• Products Intro:Product Name:Captopril
  CAS:62571-86-2
  Purity:>=98% Package:1KG/5KG/25KG或按需要包装 Remarks:100KG
• CB Index:58
• Related Information:Catalog(1995)

• Company Name:J & K SCIENTIFIC LTD.
• Tel:010-82848833 400-666-7788
• Products Intro:Product Name:Captopril, 98%, an angiotensin-converting enzyme (ACE) inhibitor
  CAS:62571-86-2
  Purity:98% Package:5G More...
• CB Index:76
• Related Information:Catalog(96815)

• Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
• Tel:4006608290; 18621169109
• Products Intro:Product Name:Captopril
  CAS:62571-86-2
  Purity:>98.0%(LC)(T) Package:5g;25g Remarks:C1580 More...
• CB Index:62
• Related Information:Catalog(40241)

• Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
• Tel:821-50328103-801 18930552037
• Products Intro:Product Name:Captopril
  CAS:62571-86-2
  Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More...
• CB Index:69
• Related Information:Catalog(15848)

• Company Name:TCI (Shanghai) Development Co., Ltd.
• Tel:021-67121386
• Products Intro:Product Name:Captopril
  CAS:62571-86-2
  Purity:98.0% LC&T Package:25G,5G More...
• CB Index:81
• Related Information:Catalog(24539)

• Company Name:BeiJing Hwrk Chemicals Limted
• Tel:0757-86329057 18501085097
• Products Intro:Product Name:Captopril
  CAS:62571-86-2
  Purity:98.00% Package:100g Remarks:HWG12051
• CB Index:55
• Related Information:Catalog(7583)