Ziprasidone

• Product Name:Ziprasidone
• Synonyms: Ziprasidone CP-88059：CP-88059-1 1,2-Benzisothiazole, 3-(1-piperazinyl)-, monohydrochlorideH-indol-2-one, 6-chloro-5-(2-chloroethyl)-1,3-dihydro 5-(2-(4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one Ziprasidone HBr 5-{2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-2,3-dihydro-1H-indol-2-one Ziprasidone solution 5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one
• CAS:146939-27-7
• MF:C21H21ClN4OS
• MW:412.94
• EINECS:203-794-9
• Mol File:146939-27-7.mol
• 

Ziprasidone, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one, is available as the hydrochloride monohydrate for oral administration (Geodon) and as the mesylate trihydrate saltfor intramuscular (IM) injection. The compound is well absorbedwith peak plasma levels occurring at 6 to 8 hours afteroral administration. The oral absorption is enhanced approximatelytwofold in the presence of food. Ziprasidone isbound about 99% to plasma proteins, primarily to albuminand α1-acid glycoprotein. Ziprasidone is not displaced in thepresence of two highly protein bound drugs, warfarin andpropranolol. Ziprasidone is extensively metabolized withonly about 5 % of the drug excreted unchanged.23 In humans,two major pathways are responsible for the metabolism ofziprasidone: (a) oxidation by CYP3A4 (one third) and (b) reductionby aldehyde oxidase (two thirds).The combinedaction of these metabolic pathways leads to four majorcirculating metabolites: benzisothiazole piperazine sulfoxide(BITP-sulfoxide), benzisothiazole piperazine sulfone (BITPsulfone),ziprasidone sulfoxide, and S-methyldihydroziprasidone.

• Ziprasidone
• 
• US $1.00-0.50/kg
• CAS:146939-27-7
• Min. Order: 1kg
• Purity: 99%
• Supply Ability: 200
• 2024-12-18

• Ziprasidone
• 
• US $1910.00 /Kg/Bag
• CAS:146939-27-7
• Min. Order: 1KG
• Purity: 99%
• Supply Ability: 100kg
• 2024-11-14

• Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
• Tel:821-50328103-801 18930552037
• Products Intro:Product Name:Ziprasidone
  CAS:146939-27-7
  Purity:98% HPLC Package:1g;5g;25g;100g More...
• CB Index:69
• Related Information:Catalog(15839)

• Company Name:TCI (Shanghai) Development Co., Ltd.
• Tel:021-67121386
• Products Intro:Product Name:Ziprasidone
  CAS:146939-27-7
  Purity:98.0% LC Package:100MG,1G More...
• CB Index:81
• Related Information:Catalog(24529)

• Company Name:Adamas Reagent, Ltd.
• Tel:400-6009262 16621234537
• Products Intro:Product Name:Ziprasidone
  CAS:146939-27-7
  Purity:对照品 Package:10mg~500mg Remarks:AC000437000
• CB Index:59
• Related Information:Catalog(14103)

• Company Name:Nanjing Chemlin Chemical Co., Ltd
• Tel:025-83697070
• Products Intro:Product Name:5-(2-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one
  CAS:146939-27-7
  Purity:98% Package:100mg; 1g; 5g; 50g; 500g; 5kg More...
• CB Index:64
• Related Information:Catalog(19179)

• Company Name:Hangzhou Yuhao Chemical Technology Co., Ltd
• Tel:0571-82693216
• Products Intro:Product Name:Ziprasidone
  CAS:146939-27-7
  More...
• CB Index:52
• Related Information:Catalog(9387)