Bleomycin
11056-06-7 Basic informationMore
- Product Name:Bleomycin
- Synonyms: Bleo Bleocin BleoMycin sulphate(Mycin series) Anti-Bloom Syndrome, N-Terminal antibody produced in rabbit DNA helicase RecQ protein-like 3 RecQ-like type 2 BLEO BLEXANE
- CAS:11056-06-7
- MF:C110H168N34O46S7
- MW:2927.17
- EINECS:232-925-2
- Mol File:11056-06-7.mol
-
USE
Bleomycin is a glycopeptide antibiotic complex isolatedfrom Streptomyces verticillus initially by Umezawa.Atleast 13 different fractions of bleomycin have been isolatedwith the clinically used product (Blenoxane) being a mixtureof predominantly A2<sub>2</sub> (55%–70%) and B<sub>2</sub> (25%–32%)fractions.Of these fractions, A<sub>2</sub> appears to possessthe greatest antineoplastic activity. Copper is found inthe naturally occurring material, and its removal is importantfor the material used clinically because it significantlyreduces activity.<br/>Bleomycin is notable for its lack of myelotoxicity, andthis allows it to be combined with other myelosuppressantswithout a resulting additive effect. The acute toxicities seenwith bleomycin are erythema (reddening of the skin), hyperpigmentation(skin darkening) found predominately on theextremities, and pulmonary toxicity. The pulmonary toxicitymay first occur as pneumonitis (inflammation of lung tissue),which normally responds to glucocorticosteroid therapy.Chronic pulmonary toxicity is expressed as pulmonaryfibrosis, which is irreversible and limits utility of the agent.
Lastest Price from Bleomycin manufacturers
- Bleomycin
-
- US $0.00-0.00/mg
- CAS:11056-06-7
- Min. Order: 1mg
- Purity: 98%
- Supply Ability: 10g/month
- 2025-02-06
- Bleomycin
-
- US $0.00-0.00/kg
- CAS:11056-06-7
- Min. Order: 1kg
- Purity: 99.9%
- Supply Ability: 20 tons
- 2023-11-01
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- Company Name:Adamas Reagent, Ltd.
- Tel:400-6009262 16621234537
- Products Intro:Product Name:Bleomycin
CAS:11056-06-7
Purity:对照品 Package:10mg~500mg Remarks:AC000979000 - CB Index:59
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- Company Name:Sichuan Kulinan Technology Co., Ltd
- Tel:400-1166-196 18981987031
- Products Intro:Product Name:Bleomycin
CAS:11056-06-7
Purity:99% HPLC Package:10g;50g;100g;500g;1kg;5kg;25kg More... - CB Index:57
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- Company Name:Chengdu Ai Keda Chemical Technology Co., Ltd.
- Tel:4008-755-333 18080918076
- Products Intro:Product Name:BleoMycin
CAS:11056-06-7
Purity:HPLC;GR;AR;CP Package:5g;25g;100g;500g More... - CB Index:55
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- Company Name:Shanghai Topbiochem Technology Co., Ltd
- Tel:021-58170097
- Products Intro:Product Name:Bleomycin
CAS:11056-06-7
Purity:98% Package:25g;100g;500g;1kg - CB Index:58
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- Company Name:Beijing Jin Ming Biotechnology Co., Ltd.
- Tel:010-60605840 18892239720
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Purity:100mg/ml Package:1.25mL - CB Index:58
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