Verapamil
52-53-9 Basic informationMore
- Product Name:Verapamil
- Synonyms: -2-isopropyl- 2-isopropyl- 4-dimethoxy-alpha-(1-methylethyl)-l)- 5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylv Benzeneacetonitrile, .alpha.-3-2-(3,4-dimethoxyphenyl)ethylmethylaminopropyl-3,4-dimethoxy-.alpha.-(1-methylethyl)- Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)- (9CI) dl-Verapamil NSC 272306NA
- CAS:52-53-9
- MF:C27H38N2O4
- MW:454.61
- EINECS:200-145-1
- Mol File:52-53-9.mol
USE
Verapamil, 5-[. Hemodynamically, verapamil causesa change in the preload, afterload, contractility, heart rate,and coronary blood flow. The drug reduces systemic vascularresistance and mean blood pressure, with minor effectson cardiac output.<br/>Verapamil is a synthetic compound possessing slightstructural similarity to papaverine. It can be separated intoits optically active isomers, of which the levorotatory enantiomeris the most potent. It is absorbed rapidly after oraladministration. The drug is metabolized quickly and, as aresult, has low bioavailability. The liver is the main siteof first-pass metabolism, forming several products. Thepreferential metabolic step involves N-dealkylation, followedby O-demethylation, and subsequent conjugation ofthe product before elimination. The metabolites have no significantbiological activity. Verapamil has an eliminationhalf-life of approximately 5 hours.
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- Company Name:Chengdu Saint - Kay Biotechnology Co., Ltd.
- Tel:028-85157043 15882256948
- Products Intro:Product Name:Verapamil
CAS:52-53-9
Purity:98% Package:MG G More... - CB Index:58
- Related Information:Catalog(4397)
- Company Name:Daicel Chiral Technologies (China)CO.,LTD
- Tel:021-50460086-9 15921403865
- Products Intro:Product Name:2-(3,4-dimethoxyphenyl)-5-((4-hydroxy-3-methoxyphenethyl)(methyl)amino)-2-isopropylpentanenitrile
Purity:95% HPLC Package:10MG ;25MG;50MG;100MG Remarks:DCTI-C-1189 - CB Index:65
- Related Information:Catalog(7195)
- Company Name:Shanghai Sphchem Co., Ltd.
- Tel:021-56491756 13512199871
- Products Intro:
- CB Index:55
- Related Information:Catalog(4000)
- Company Name:Shanghai Topbiochem Technology Co., Ltd
- Tel:021-58170097
- Products Intro:Product Name:verapamil
CAS:52-53-9
Purity:98% Package:25g;100g;1kg - CB Index:58
- Related Information:Catalog(9458)