Verapamil
52-53-9 Basic informationMore
- Product Name:Verapamil
- Synonyms: -2-isopropyl- 4-dimethoxy-alpha-(1-methylethyl)-l)- 5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylv Benzeneacetonitrile, .alpha.-3-2-(3,4-dimethoxyphenyl)ethylmethylaminopropyl-3,4-dimethoxy-.alpha.-(1-methylethyl)- Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)- (9CI) dl-Verapamil NSC 272306NA R,S-Verapamil
- CAS:52-53-9
- MF:C27H38N2O4
- MW:454.61
- EINECS:200-145-1
- Mol File:52-53-9.mol
-
USE
Verapamil, 5-[. Hemodynamically, verapamil causesa change in the preload, afterload, contractility, heart rate,and coronary blood flow. The drug reduces systemic vascularresistance and mean blood pressure, with minor effectson cardiac output.<br/>Verapamil is a synthetic compound possessing slightstructural similarity to papaverine. It can be separated intoits optically active isomers, of which the levorotatory enantiomeris the most potent. It is absorbed rapidly after oraladministration. The drug is metabolized quickly and, as aresult, has low bioavailability. The liver is the main siteof first-pass metabolism, forming several products. Thepreferential metabolic step involves N-dealkylation, followedby O-demethylation, and subsequent conjugation ofthe product before elimination. The metabolites have no significantbiological activity. Verapamil has an eliminationhalf-life of approximately 5 hours.
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- Company Name:Chengdu Saint - Kay Biotechnology Co., Ltd.
- Tel:028-85157043 15882256948
- Products Intro:Product Name:Verapamil
CAS:52-53-9
Purity:98% Package:MG G More... - CB Index:58
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- Company Name:Syntechem Co.,Ltd
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- Products Intro:Product Name:5-((3,4-diMethoxyphenethyl)(Methyl)aMino)-2-(3,4-diMethoxyphenyl)-2-isopropylpentanenitrile
CAS:52-53-9
Purity:97% Package:1g;5g;25g;100g;250g;1kg;5kg;10kg;25kg Remarks:we offer low price custom synthesis and contract manufacturing More... - CB Index:57
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- Company Name:Shanghai Sphchem Co., Ltd.
- Tel:021-56491756 13512199871
- Products Intro:Product Name:Verapamil
- CB Index:55
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- Company Name:Spectrum Chemical Manufacturing Corp.
- Tel:021-021-021-67601398-809-809-809 15221380277
- Products Intro:Product Name:VERAPAMIL HYDROCHLORIDE
CAS:52-53-9
Package:1GM Remarks:MP-0219554501 More... - CB Index:60
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- Company Name:Wuhan Haizheng Industry & Trade Development Co. Ltd
- Tel:027-8866 0053/88660577/88660578
- Products Intro:Product Name:VerapaMil
CAS:52-53-9
Purity:98% Package:1g;5g;10g;50g;100g;500g;1kg More... - CB Index:55
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- Company Name:Beijing HuaMeiHuLiBiological Chemical
- Tel:010-56205725
- Products Intro:Product Name:VerapaMil
CAS:52-53-9
Purity:99% Package:25kg More... - CB Index:58
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- Company Name:Shanghai Topbiochem Technology Co., Ltd
- Tel:021-58170097
- Products Intro:Product Name:verapamil
CAS:52-53-9
Purity:98% Package:25g;100g;1kg - CB Index:58
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- Company Name:Guangzhou Isun Pharmaceutical Co., Ltd
- Tel:020-39119399 18927568969
- Products Intro:Product Name:Verapamil
CAS:52-53-9
Purity:98% Package:1G; 5G; 25G; 100G; 1KG; 5KG - CB Index:55
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