Anagliptin
739366-20-2 Basic informationMore
- Product Name:Anagliptin
- Synonyms: Anagliptin N-[2-[[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]aMino]-2-Methylpropyl]-2-Methyl-6-pyrazolo[1,5-a]pyriMidinecarboxaMide Anagliptin API Suiny (S)-N-(2-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylaMino)-2-Methylpropyl)-2-Methylpyrazolo[1,5-a]pyriMidine-6-carboxaMide N-[2-[[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]amino]-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide (R)-N-(2-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)-2-methylpropyl)-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide N-[2-[[2-[(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide
- CAS:739366-20-2
- MF:C19H25N7O2
- MW:383.45
- EINECS:
- Mol File:739366-20-2.mol
USE
Anagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that was approved
in Japan in November 2012 for the treatment of patients with Type 2 diabetes
mellitus (T2DM).
Anagliptin (also known asSK-0403) is a treatment for diabetes based on inhibition of DPP-4, an enzyme that is responsible for degradation of glucagon-like peptide 1 (GLP-1), a 30-amino acid peptide that is secreted in response to food intake. GLP-1 stimulates
insulin secretion and inhibits glucagon secretion, which leads to lower
levels of plasma glucose. Following the introduction of the first DPP-4 inhibitor, sitagliptin, in 2006, several members of the gliptin class have been approved worldwide. Anagliptin was discovered from an effort to replace
a metabolically labile isoindoline group from an earlier DPP-4 inhibitor series with a stable bioisostere. Anagliptin is a potent DPP-4 inhibitor, with an IC<sub>50</sub>=3.8 nM and >10,000-fold selectivity over inhibition of DPP-8 and DPP-9.
Lastest Price from Anagliptin manufacturers
- Anagliptin
- US $5.00-0.10/KG
- CAS:739366-20-2
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- 2024-04-16
- Anagliptin
- US $50.00 /kg
- CAS:739366-20-2
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 50 tons
- 2024-02-27
Browse by Nationality 739366-20-2 Suppliers >Global suppliers
Beijing (2) Shanghai (28) Chongqing (1) Sichuan (2) Guangdong (9) Zhejiang (7) Fujian (1) Hubei (15) Shandong (3) Henan (3) Hebei (2) Anhui (4) Jiangsu (14) Jiangxi (1) Shaanxi (5) Hong Kong (1) Member (96) All (98)
Please select the suppliers
Recommend You Select Member Companies
Recommend You Select Member Companies
- Company Name:Chengdu Novel Biomedical Co., Ltd.
- Tel:028-85255396 18302801538
- Products Intro:Product Name:Anagliptin
CAS:739366-20-2
Purity:95% Package:25MG/1000.00; More... - CB Index:58
- Related Information:Catalog(2238)
- Company Name:Nanjing Chemlin Chemical Co., Ltd
- Tel:025-83697070
- Products Intro:Product Name:(S)-N-(2-((2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl)amino)-2-methylpropyl)-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide
CAS:739366-20-2
Purity:98% Package:100mg;1g;10g;100g;1kg More... - CB Index:64
- Related Information:Catalog(17987)
- Company Name:Nanjing Sunlida Biological Technology Co., Ltd.
- Tel:025-57798810
- Products Intro:Product Name:Anagliptin
CAS:739366-20-2
Purity:97% Remarks:SLD-0735 More... - CB Index:55
- Related Information:Catalog(3750)
- Company Name:TargetMol Chemicals Inc.
- Tel:021-33632979 15002134094
- Products Intro:Product Name:Anagliptin
CAS:739366-20-2
Package:1 mL;10 mg;2 mg;25 mg;5 mg;50 mg Remarks: 90+%,具体纯度信息请见官网 - CB Index:58
- Related Information:Catalog(7934)
- Company Name:Finetech Industry Limited
- Tel:027-87465837 19945049750
- Products Intro:Product Name:Anagliptin
CAS:739366-20-2
Purity:98% Package:1g,10g,25g,500g,1kg - CB Index:58
- Related Information:Catalog(9636)