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Anagliptin

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739366-20-2 Basic informationMore
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Anagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that was approved in Japan in November 2012 for the treatment of patients with Type 2 diabetes mellitus (T2DM). Anagliptin (also known asSK-0403) is a treatment for diabetes based on inhibition of DPP-4, an enzyme that is responsible for degradation of glucagon-like peptide 1 (GLP-1), a 30-amino acid peptide that is secreted in response to food intake. GLP-1 stimulates insulin secretion and inhibits glucagon secretion, which leads to lower levels of plasma glucose. Following the introduction of the first DPP-4 inhibitor, sitagliptin, in 2006, several members of the gliptin class have been approved worldwide. Anagliptin was discovered from an effort to replace a metabolically labile isoindoline group from an earlier DPP-4 inhibitor series with a stable bioisostere. Anagliptin is a potent DPP-4 inhibitor, with an IC<sub>50</sub>=3.8 nM and >10,000-fold selectivity over inhibition of DPP-8 and DPP-9.
Lastest Price from Anagliptin manufacturers
  • Anagliptin
  • US $5.00-0.10/KG
  • CAS:739366-20-2
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: g-kg-tons, free sample is available
  • 2024-04-16
  • Anagliptin
  • US $50.00 /kg
  • CAS:739366-20-2
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 50 tons
  • 2024-02-27

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  • Company Name:Chengdu Novel Biomedical Co., Ltd.
  • Tel:028-85255396 18302801538
  • Products Intro:Product Name:Anagliptin
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  • Company Name:Nanjing Sunlida Biological Technology Co., Ltd.
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  • Company Name:TargetMol Chemicals Inc.
  • Tel:021-33632979 15002134094
  • Products Intro:Product Name:Anagliptin
    CAS:739366-20-2
    Package:1 mL;10 mg;2 mg;25 mg;5 mg;50 mg Remarks: 90+%,具体纯度信息请见官网
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  • Company Name:Finetech Industry Limited
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    Purity:98% Package:1g,10g,25g,500g,1kg
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