Anagliptin

• Product Name:Anagliptin
• Synonyms: Anagliptin N-[2-[[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]aMino]-2-Methylpropyl]-2-Methyl-6-pyrazolo[1,5-a]pyriMidinecarboxaMide Anagliptin API Suiny (S)-N-(2-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylaMino)-2-Methylpropyl)-2-Methylpyrazolo[1,5-a]pyriMidine-6-carboxaMide N-[2-[[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]amino]-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide (R)-N-(2-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)-2-methylpropyl)-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide N-[2-[[2-[(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide
• CAS:739366-20-2
• MF:C19H25N7O2
• MW:383.45
• EINECS:
• Mol File:739366-20-2.mol
• 

Anagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that was approved in Japan in November 2012 for the treatment of patients with Type 2 diabetes mellitus (T2DM). Anagliptin (also known asSK-0403) is a treatment for diabetes based on inhibition of DPP-4, an enzyme that is responsible for degradation of glucagon-like peptide 1 (GLP-1), a 30-amino acid peptide that is secreted in response to food intake. GLP-1 stimulates insulin secretion and inhibits glucagon secretion, which leads to lower levels of plasma glucose. Following the introduction of the first DPP-4 inhibitor, sitagliptin, in 2006, several members of the gliptin class have been approved worldwide. Anagliptin was discovered from an effort to replace a metabolically labile isoindoline group from an earlier DPP-4 inhibitor series with a stable bioisostere. Anagliptin is a potent DPP-4 inhibitor, with an IC₅₀=3.8 nM and >10,000-fold selectivity over inhibition of DPP-8 and DPP-9.

• Anagliptin
• 
• US $5.00-0.10/KG
• CAS:739366-20-2
• Min. Order: 1KG
• Purity: 99%
• Supply Ability: g-kg-tons, free sample is available
• 2024-04-16

• Anagliptin
• 
• US $15.00-10.00/KG
• CAS:739366-20-2
• Min. Order: 1KG
• Purity: 99%+ HPLC
• Supply Ability: Monthly supply of 1 ton
• 2021-07-13

• Company Name:Nanjing Chemlin Chemical Co., Ltd
• Tel:025-83697070
• Products Intro:Product Name:(S)-N-(2-((2-(2-Cyanopyrrolidin-1-yl)-2-oxoethyl)amino)-2-methylpropyl)-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide
  CAS:739366-20-2
  Purity:98% Package:100mg; 1g; 10g; 100g; 1kg More...
• CB Index:64
• Related Information:Catalog(19179)

• Company Name:Nanjing Sunlida Biological Technology Co., Ltd.
• Tel:025-57798810
• Products Intro:Product Name:Anagliptin
  CAS:739366-20-2
  Purity:97% Package:1g;5g;25g;100g Remarks:SLD-0735 More...
• CB Index:55
• Related Information:Catalog(3239)

• Company Name:Nanjing Duolong Bio-tech Co.,Ltd.
• Tel: 18905173768
• Products Intro:Product Name:Anagliptin
  CAS:739366-20-2
  Purity:97% Package:1g;10g;100g;1kg More...
• CB Index:50
• Related Information:Catalog(2331)

• Company Name:Zhengzhou Alfachem Co., Ltd.
• Tel:0371-53765687 18937137882
• Products Intro:Product Name:(S)-N-(2-((2-(2-Cyanopyrrolidin-1-yl)-2-oxoethyl)amino)-2-methylpropyl)-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide
  CAS:739366-20-2
  Purity:98%
• CB Index:55
• Related Information:Catalog(7977)