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α-Lipoic Acid

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1077-28-7 Basic informationMore
USE
Lipoic acid(ALA), also known as α-lipoic acid (alpha-lipoic acid) or thioctic acid, has the formula C<sub>8</sub>H<sub>14</sub>S<sub>2</sub>O<sub>2</sub> and systematic name 5-(1,2-dithiolan-3-yl)pentanoic acid. It contains a disulfide group, which can be transformed in the body to a dithiol group.<br/> ALA has been on the market since the 1950s as a dietary supplement. It is a natural antioxidant usually made by the body. The advantage of ALA over other antioxidants such as vitamin C and E is that it is soluble both in water and in fat. Researchers in the former Soviet Union found that ALA can chelate mercury once it is transformed into the dithiol-containing compound. ALA can penetrate both the blood–brain barrier and the cell membrane and therefore would be a very interesting chelating agent. Nevertheless, there is much debate about its mode of action, side effects and effectiveness. Other antidotes, such as BAL and DMSA, are more efficient in the removal of heavy metals. ALA has not received FDA approval as a chelating agent, but it is still sold as a food supplement.
Lastest Price from α-Lipoic Acid manufacturers
  • α-Lipoic Acid
  • US $50.00 /kg
  • CAS:1077-28-7
  • Min. Order: 1kg
  • Purity: 99
  • Supply Ability: 5000
  • 2024-12-24

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