Tafenoquine
106635-80-7 Basic informationMore
- Product Name:Tafenoquine
- Synonyms: Tafenoquine 4-[5-[3-(Trifluoromethyl)phenoxy]-2,6-dimethoxy-4-methyl-8-quinolinylamino]-1-pentanamine 8-[(4-Amino-1-methylbutyl)amino]-2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinoline N4-(2,6-diMethoxy-4-Methyl-5-(3-(trifluoroMethyl)phenoxy)quinolin-8-yl)pentane-1,4-diaMine N4-{2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]-8-quinolinyl}-1,4-pentanediamine WR 238605; WR238605; WR-238605; SB-252263; SB 252263; SB252263 WR-238605, WR 238605, WR238605, SB-252263-AAB; SB252263-AAB; SB 252263-AAB; TAFENOQUINE; KRINTAFE Krintafe
- CAS:106635-80-7
- MF:C24H28F3N3O3
- MW:463.49
- EINECS:
- Mol File:106635-80-7.mol
-
USE
Etaquine. A synthetic 8-aminoquinoline, formulated as the
succinate for oral administration. Tafenoquine is an effective
schizonticide against P. falciparum and P. vivax. It is also
active against the pre-erythrocytic stages of these species and
the hypnozoites of P. vivax. A dosage of 100 mg base corresponds
to 125 mg salt. Oral absorption is slow with a maximum
plasma concentration reached after 12 h. The half-life is
2 weeks, significantly longer than that of primaquine. It is not
eliminated via the kidneys. Toxicity and side effects are similar
to those of primaquine. Development of methemoglobinemia
is common. Patients with G6PD deficiency may develop
severe hemolysis.<br/>
It is in clinical development for the treatment and prophylaxis
of P. vivax malaria and for the treatment of P. falciparum
infection.
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- Company Name:WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
- Tel:17702719238 17702719238
- Products Intro:Product Name:Tafenoquine
CAS:106635-80-7
Purity:98% HPLC Package:50.0mg;100.0mg; 200.0mg;500mg;1g;5g; 10g More... - CB Index:64
- Related Information:Catalog(918)
- Company Name:Shanghai Hekang Biotechnology Co., Ltd.
- Tel: 18939837085
- Products Intro:Product Name:Tafenoquine succinate
CAS:106635-80-7
Purity:98+% Package:1g, 5g, 10g, 25g, 100g, 1kg, 1000kg Remarks:C0164 More... - CB Index:55
- Related Information:Catalog(1823)
- Company Name:Beijing Jin Ming Biotechnology Co., Ltd.
- Tel:010-60605840 18892239720
- Products Intro:Product Name:Tafenoquine
CAS:106635-80-7
Purity:97% Package:1mg;5mg;10mg;25mg - CB Index:58
- Related Information:Catalog(12308)