PROTEIN C
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- Product Name:PROTEIN C
- Synonyms: PROTEIN C SOLUTION Recombinant Human Activated Protein C 4-[(4-Carboxybutyl)amino]-1-piperidinecarboxylic Acid (4S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl Ester 7-Ethyl-10-(4-N-aminopentanoic acid)-1-piperidino)carbonyloxycamptothecin Drotrecogin Alfa ACTIVATED HUMAN PROTEIN C PROTEIN C, ACTIVATED, HUMAN PLASMA PROTEIN C, HUMAN
- CAS:60202-16-6
- MF:C33H38N4O8
- MW:0
- EINECS:
- Mol File:Mol File
USE
Drotrecogin alfa (activated), drotrecoginalfa (activated; Xigris), is a recombinant form of humanactivated protein C. Activated protein C exerts an antithromboticeffect by inhibiting factors Va and VIIIa. In vitro dataindicate that activated protein C has indirect profibrinolyticactivity through its ability to inhibit plasminogen activator inhibitor-1 (PAI-1) and to limit generation of activated thrombin-activatable fibrinolysis inhibitor. Additionally, in vitrodata indicate that activated protein C may exert an antiinflammatoryeffect by inhibiting TNF production by monocytes,by blocking leukocyte adhesion to selectins, and bylimiting the thrombin-induced inflammatory responses withinthe microvascular epithelium.Vials of drotrecogin alfa should be stored at 2°C to 8°Cwithout freezing. The reconstituted solution is stable for14 hours at 25°C.
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- Company Name:Career Henan Chemica Co
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- Products Intro:Product Name:PROTEIN C
CAS:60202-16-6
Purity:98% HPLC Package:25KG;100USD - CB Index:58
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CAS:60202-16-6
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