Pramlintide acetate

• Product Name:Pramlintide acetate
• Synonyms: AMYLIN (HUMAN), 25-L-PROLINE-28-L-PROLINE-29-L-PROLINE-, ACETATE (SALT), HYDRATE pramlintide acetate pramlintide acetate hydrate 25-L-Proline-28-L-proline-29-L-proline-aMylin (huMan) Acetate Hydrate AC-137 Acetate Hydrate, SyMlin Acetate Hydrate Tripo-aMylin Acetate Hydrate Pramlintide Acetate, Amylin Rat Pramlintide?Acetate impurity
• CAS:196078-30-5
• MF:C173H273N51O56S2
• MW:4027.46
• EINECS:251-228-4
• Mol File:196078-30-5.mol
• 

<p>Pramlintide acetate is White Solid</p> <p>Pramlintide acetate is an analogue of human amylin used in the treatment of insulin dependent diabetes.</p> <p>Pramlintide acetate is an injectable human amylin analog that has been launched for the treatment of both type 1 and type 2 diabetes, in conjunction with insulin. While it is also a 37-amino acid peptide, it differs from its parent predecessor by the substitution of Ala-25, Ser-28, and Ser-29 with prolines. Not only do these modifications improve the solubility of the peptide, they also eliminate the aggregation observed with amylin, resulting in a stable synthetic analog with retention of biological activity that is suitable for pharmaceutical use. As an indication of potency, Pramlintide acetate inhibits the binding of radioiodinated rat amylin to rat nucleus accumbens membranes with a Ki value of 23 pM. Its mechanism of action mimics amylin; as a neurohormone that is cosecreted with insulin from the pancreatic β cells in response to meals, it is involved in glucose homeostasis. Both peptides lower postprandial glucose levels by inhibiting glucagon and by restraining the vagus-mediated rate of gastric emptying, thereby, slowing intestinal carbohydrate absorption. Furthermore, amylin, orPramlintide acetate, has the added benefit of inducing postprandial satiety resulting in weight loss in the patients with type 2 diabetes. Since Pramlintide acetate slows gastric emptying, it is contraindicated in patients with gastroparesis and in patients taking drugs that alter gastrointestinal motility (anticholinergic agents, such as, atropine) or slow down the intestinal absorption of nutrients (such as α-glucosidase inhibitors). Pramlintide acetate is also contraindicated in patients with hypoglycemic tendencies; due to co-administration with insulin, severe insulin-induced hypoglycemia is a risk. The most commonly reported adverse events include nausea, vomiting, anorexia, headache, abdominal pain, fatigue, dizziness, coughing, and pharyngitis.</p>

• Pramlintide acetate
• 
• US $0.00 /g
• CAS:196078-30-5
• Min. Order: 1g
• Purity: 98%min
• Supply Ability: 1000g
• 2024-11-21

• Pramlintide acetate
• 
• US $999.00-666.00/kg
• CAS:196078-30-5
• Min. Order: 1kg
• Purity: 99%
• Supply Ability: 5000
• 2024-11-21

• Company Name:Shaoxing Junyu Biotechnology Co., LTD
• Tel:0571-88211921 15572296305
• Products Intro:Product Name:PramlintideAcetate
  CAS:196078-30-5
  Purity:0.98 Package:1mg/RMB 100;10mg/RMB 388;50mg/RMB 588 Remarks:kg
• CB Index:58
• Related Information:Catalog(5128)

• Company Name:Zhejiang Jiekun Biotechnology Co., Ltd
• Tel:0571-88211951 13735575465
• Products Intro:Product Name:Pramlintide Acetate
  CAS:196078-30-5
  Package:1mg/RMB 78;10mg10mg
• CB Index:58
• Related Information:Catalog(4904)

• Company Name:Phygene
• Tel: 18059081430
• Products Intro:Product Name:Pramlintide Acetate
  CAS:196078-30-5
  Purity:95%-99% Package:1mg；10mg；50mg；100mg；1g；100g；1kg
• CB Index:58
• Related Information:Catalog(1232)

• Company Name:J & K SCIENTIFIC LTD.
• Tel:010-82848833 400-666-7788
• Products Intro:Product Name:PraMlintide Acetate Hydrate
  CAS:196078-30-5
  Package:2.5Mg,25Mg More...
• CB Index:76
• Related Information:Catalog(94657)

• Company Name:Alabiochem Tech.Co., Ltd.
• Tel:0512-58900862 400-0707518
• Products Intro:Product Name:Pramlintide
  CAS:196078-30-5
  Purity:99% Package:25mg; 50mg;250mg;Bulk Remarks:B0367
• CB Index:59
• Related Information:Catalog(995)

• Company Name:Chembest Research Laboratories Limited
• Tel:+86-21-20908456
• Products Intro:Product Name:PraMlintide Acetate
  CAS:196078-30-5
  Remarks:C14049 More...
• CB Index:61
• Related Information:Catalog(6005)