Bupivacaine
2180-92-9 Basic informationMore
- Product Name:Bupivacaine
- Synonyms: (.+/-.)-1-Butyl-2',6'-pipecoloxylidide 1-Butyl-2-(2,6-xylycarbamoyl)piperidine 1-Butyl-2',6'-pipecoloxylidide 1-butyl-2’,6’-pipecoloxylidide 1-butyl-n-(2,6-dimethylphenyl)-2-piperidinecarboxamid Bupivacaine Base & HCL Bupivacaine anhydrous Bupivacaine (USP)
- CAS:2180-92-9
- MF:C18H28N2O
- MW:288.43
- EINECS:218-553-3
- Mol File:2180-92-9.mol
USE
Bupivacaine was synthesized simultaneously with mepivacainein 1957 but was at first overlooked because of the increasedtoxicity compared with mepivacaine. When themethyl on the cyclic amine of mepivacaine is exchanged fora butyl group the lipophilicity, potency and the duration ofaction all increase. Literature reports of cardiovascular toxicity,including severe hypotension and bradycardia, areabundant in the literature.91 Bupivacaine is highly bound toplasma proteins (95%), and thus the free concentration mayremain low until all of the protein binding sites are occupied.After that point, the plasma levels of bupivacaine rise rapidlyand patients may progress to overt cardiac toxicity withoutever showing signs of CNS toxicity. The cardiotoxicity ofbupivacaine is a result of its affinity to cardiac tissues and itsability to depress electrical conduction and predispose theheart to reentry types of arrhythmias. The cardiotoxicity ofbupivacaine was found to be significantly more prominentwith the “R” isomer, or the racemic mixture, thus the “S”stereoisomer is now on the market as levobupivacaine.
Lastest Price from Bupivacaine manufacturers
- Bupivacaine
- US $50.00-100.00/G
- CAS:2180-92-9
- Min. Order: 10G
- Purity: 98%
- Supply Ability: 2000KG
- 2024-12-04
- Bupivacaine
- US $0.00-0.00/KG
- CAS:2180-92-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 500
- 2024-11-27
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- Company Name:Changzhou Sunchem Pharmaceutical Chemical Material Co.,Ltd.
- Tel:0519-85195575 15861192208
- Products Intro:Product Name:Bupivacaine
CAS:2180-92-9
Purity:99.5% More... - CB Index:69
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- Company Name:BeiJing Hwrk Chemicals Limted
- Tel:0757-86329057 18934348241
- Products Intro:Product Name:Bupivacaine
CAS:2180-92-9
Purity:98.00% Package:25g More... - CB Index:55
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- Company Name:Adamas Reagent, Ltd.
- Tel:400-6009262 16621234537
- Products Intro:Product Name:Bupivacaine
CAS:2180-92-9
Purity:对照品 Package:10mg~500mg Remarks:AC000144000 More... - CB Index:59
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- Company Name:Jinan Chenghui Shuangda biological Co., LTD
- Tel:0531-58897003 15550412551
- Products Intro:Product Name:Bupivacaine
CAS:2180-92-9
Purity:99% Package:1kg;5kg;25kg - CB Index:62
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- Company Name:Dalian Meilun Biotech Co., Ltd.
- Tel:0411-62910999 13889544652
- Products Intro:Product Name:Bupivacaine
CAS:2180-92-9
Purity:>98% Package:25 G Remarks:500 More... - CB Index:58
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- Company Name:S.Z. PhyStandard Bio-Tech. Co., Ltd.
- Tel:0755-4000505016 13380397412
- Products Intro:Product Name:Bupivacaine
CAS:2180-92-9
Purity:99% HPLC Package:10mg;25mg;50mg;100mg - CB Index:50
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