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Thioridazine hydrochloride

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USE
Thioridazine hydrochloride,10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine monohydrochloride (Mellaril), is amember of the piperidine subgroup of the phenothiazines.The drug has a relatively low tendency to produce EPS. Thedrug has high anticholinergic activity, and this activity in thestriatum, counterbalancing a striatal DA block, may be responsiblefor the low EPS. It also has been suggested thatthere may be increased DA receptor selectivity, which may be responsible. The drug has sedative and hypotensive activityin common with chlorpromazine and less antiemeticactivity. At high doses, pigmentary retinopathy has been observed.Its major metabolites include N-demethylated, ringhydroxylated,and S-oxidized products. Thioridazine isprominently converted to the active metabolite mesoridazine(discussed next), which probably contributes to the antipsychoticactivity of thioridazine.
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  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:010-82848833 400-666-7788
  • Products Intro:Product Name:Thioridazine Hydrochloride
    CAS:130-61-0
    Package:1g,2.5g,25g More...
  • CB Index:76
  • Related Information:Catalog(96815)
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  • Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
  • Tel:821-50328103-801 18930552037
  • Products Intro:Product Name:Thioridazine hydrochloride;10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(Methylthio)-10H-phenothiazinehydrochloride
    CAS:130-61-0
    Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More...
  • CB Index:69
  • Related Information:Catalog(15839)
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  • Company Name:TCI (Shanghai) Development Co., Ltd.
  • Tel:021-67121386
  • Products Intro:Product Name:Thioridazine Hydrochloride
    CAS:130-61-0
    Purity:98.0% LC Package:25G,5G More...
  • CB Index:81
  • Related Information:Catalog(24529)
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