Tolvaptan
150683-30-0 Basic informationMore
- Product Name:Tolvaptan
- Synonyms: N-[4-(9-chloro-6-hydroxy-2-azabicyclo[5.4.0]undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide Tolvaptan N-[4-[(5R)-7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]-3-methylphenyl]-2-methylbenzamide N-(4-{[(5R)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}-3-Methylphenyl)-2-MethylbenzaMide OPC 41061 OPC-41061 SaMsca Tolvaptan Tablets
- CAS:150683-30-0
- MF:C26H25ClN2O3
- MW:448.94
- EINECS:691-537-5
- Mol File:150683-30-0.mol
USE
Tolvaptan(SAMSCA) should be initiated and re-initiated in patients only in a hospital where serum sodium can be monitored closely. Too rapid correction of hyponatremia (e.g., >12 mEq/L/24 hours) can cause osmotic demyelination resulting in dysarthria, mutism, dysphagia, lethargy, affective changes, spastic quadriparesis, seizures, coma and death. In susceptible patients, including those with severe malnutrition, alcoholism or advanced liver disease, slower rates of correction may be advisable.<br />
Tolvaptan(SAMSCA) is contraindicated in the following conditions:<br />
<br />
<ul>
<li>Urgent need to raise serum sodium acutely</li>
<li>Inability of the patient to sense or appropriately respond to thirst</li>
<li>Hypovolemic hyponatremia</li>
<li>Concomitant use of strong CYP 3A inhibitors</li>
<li>Anuric patients</li>
<li>Hypersensitivity (e.g. anaphylactic shock, rash generalized) to tolvaptan or its components</li>
</ul>
Lastest Price from Tolvaptan manufacturers
- Tolvaptan
- US $0.00-0.00/kg
- CAS:150683-30-0
- Min. Order: 1kg
- Purity: 99.5%
- Supply Ability: 5000
- 2024-11-21
- to Lvaptan
- US $0.00 /g
- CAS:150683-30-0
- Min. Order: 1g
- Purity: More Than 99%
- Supply Ability: 100kg/Month
- 2024-11-18
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- Company Name:Enki Biopharmaceuticals(Shanghai) Limited
- Tel:021-57680965 13916707528
- Products Intro:Product Name:Tolvaptan
CAS:150683-30-0
Purity:99.5% Package:1kg;5kg;25kg More... - CB Index:55
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- Company Name:Shifang ShengYuan Technology Co., Ltd.
- Tel:0838-6510595 13402890778 18881099744
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CAS:150683-30-0
Purity:98% HPLC Package:10g;25g;100g; More... - CB Index:56
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- Company Name:Nanjing Daqin Pharmaceutical Technology Co., Ltd.
- Tel:025-58470199 18351831988
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Purity:99% HPLC Package:100kg;10kg;1kg;10g More... - CB Index:58
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- Company Name:Nanjing Sunlida Biological Technology Co., Ltd.
- Tel:025-57798810
- Products Intro:Product Name:Tolvaptan
CAS:150683-30-0
Purity:99% Package:1g;5g;25g;100g Remarks:SLD-3039 More... - CB Index:55
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- Company Name:Nanjing Feihao Technology Co., Ltd.
- Tel:025-58855213 15366065068
- Products Intro:Product Name:N-{4-[(5RS)-7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl]-3-methylphenyl}-2-methylbenzamide
CAS:150683-30-0
Purity:99.5%HPLC,0.1% Package:1g;25g;100g;1kg;25kg More... - CB Index:58
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- Company Name:Hangzhou Kehui Pharmaceutical Co.,Ltd
- Tel:0571-87359773 18094707759
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CAS:150683-30-0
Package:1kg;10kg - CB Index:58
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- Company Name:Shandong Mopai Biotechnology Co., Ltd
- Tel: 13070690626
- Products Intro:Product Name:Tolvaptan
CAS:150683-30-0
Purity:99% Package:500G;1000G;1000G - CB Index:58
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