Diquafosol Tetrasodium
211427-08-6 Basic informationMore
- Product Name:Diquafosol Tetrasodium
- Synonyms: INS 365 D03864 Diquafosol sodium Diquafosol sodium (jan) Diquafosol tetrasodium Diquafosol tetrasodium (usan) Diquafosol Impurity 7(UP4U) [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate
- CAS:211427-08-6
- MF:C18H27N4NaO23P4
- MW:814.3
- EINECS:253-874-2
- Mol File:211427-08-6.mol
-
USE
Diquafosol (INS-365) was approved in Japan in 2010 as a 3%
ophthalmic solution for treatment of dry eye disease. Clinical diagnosis of dry eye is difficult because the condition
presents a variety of symptoms. Treatment options include tear
supplements (lubricants), anti-inflammatory drugs (e.g., cyclosporine
eye drops or steroid eye drops), and tear retention devices. Diquafosol
is a unique agent for the treatment of dry eye in that it acts as a P2Y2
purinergic receptor agonist with the ability to activate this receptor on
the ocular surface and stimulate water, lipid, and mucin secretion. Diquafosol is metabolized by phosphodiesterases to UTP, UDP, UMP, and uridine. Diquafosol has been well tolerated in clinical trials, with side effects being local to the ocular surface.In addition,no serious ocular or systemic adverse drug reactions were found
during the clinical trials.
Lastest Price from Diquafosol Tetrasodium manufacturers
- Diquafosol Sodium
-
- US $0.00 /KG
- CAS:211427-08-6
- Min. Order: 1KG
- Purity: 99%min
- Supply Ability: 10kg
- 2025-02-06
- Diquafosol Impurity 11
-
- US $0.00 /mg
- CAS:211427-08-6
- Min. Order: 1mg
- Purity: 99.88%
- Supply Ability: 50mg
- 2024-04-11
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- Company Name:Wellman Pharmaceutical Group Limited
- Tel:027-83778875 15807197853
- Products Intro:Product Name:Diquafosol
CAS:211427-08-6
Purity:99% Remarks:785g - CB Index:58
- Related Information:Catalog(4032)
- Company Name:Changzhou Red Sun Pharmaceutical Co., Ltd.
- Tel:0519-85223897 13766960291
- Products Intro:Product Name:Diquafosol tetrasodium
CAS:211427-08-6
Purity:99% HPLC Package:25KG - CB Index:58
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- Company Name:Beijing Jingzi Pharmaceutical Technology Co., Ltd.
- Tel: 15011485209
- Products Intro:Product Name:Diquafosol tetrasodium; Diquafosol tetrasodium impurity; Diquafosol tetrasodium intermediate; P1,P4-Diuridine 5'-tetraphosphate tetrasodium salt
CAS:211427-08-6
Purity:99% HPLC Package:10mg;100mg;1kg - CB Index:58
- Related Information:Catalog(81)
- Company Name:Hangzhou Hua Zhe Biological Medicine Co., LTD
- Tel:0571-5683-8096 17302275155
- Products Intro:Product Name:INS 365
CAS:211427-08-6
Purity:98%HPLC Package:5KG;1KG - CB Index:58
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- Company Name:S.Z. PhyStandard Bio-Tech. Co., Ltd.
- Tel:0755-4000505016 13380397412
- Products Intro:Product Name:Diquafosol Tetrasodium Salt
CAS:211427-08-6
Purity:99% HPLC Package:10mg;25mg;50mg;100mg - CB Index:50
- Related Information:Catalog(5047)
- Company Name:Nanjing Sunlida Biological Technology Co., Ltd.
- Tel:025-57798810
- Products Intro:CAS:211427-08-6
Purity:98% Package:1g;5g;25g;100g - CB Index:55
- Related Information:Catalog(3239)
- Company Name:TargetMol Chemicals Inc.
- Tel:021-021-33632979 15002134094
- Products Intro:Product Name:Diquafosol tetrasodium
CAS:211427-08-6
Purity:99.97% Package:1mg/RMB 256;2mg/RMB 365;5mg/RMB 592 - CB Index:58
- Related Information:Catalog(7783)