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INS 365

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211427-08-6 Basic informationMore
USE
Diquafosol (INS-365) was approved in Japan in 2010 as a 3% ophthalmic solution for treatment of dry eye disease. Clinical diagnosis of dry eye is difficult because the condition presents a variety of symptoms. Treatment options include tear supplements (lubricants), anti-inflammatory drugs (e.g., cyclosporine eye drops or steroid eye drops), and tear retention devices. Diquafosol is a unique agent for the treatment of dry eye in that it acts as a P2Y2 purinergic receptor agonist with the ability to activate this receptor on the ocular surface and stimulate water, lipid, and mucin secretion. Diquafosol is metabolized by phosphodiesterases to UTP, UDP, UMP, and uridine. Diquafosol has been well tolerated in clinical trials, with side effects being local to the ocular surface.In addition,no serious ocular or systemic adverse drug reactions were found during the clinical trials.
Lastest Price from INS 365 manufacturers
  • Diquafosol Sodium
  • US $0.00 /KG
  • CAS:211427-08-6
  • Min. Order: 1KG
  • Purity: 99%min
  • Supply Ability: 10kg
  • 2024-09-18
  • Diquafosol Impurity 11
  • US $0.00 /mg
  • CAS:211427-08-6
  • Min. Order: 1mg
  • Purity: 99.88%
  • Supply Ability: 50mg
  • 2024-04-11

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  • Company Name:Wellman Pharmaceutical Group Limited
  • Tel:027-027-83778875 15807197853
  • Products Intro:Product Name:Diquafosol
    CAS:211427-08-6
    Purity:99% Remarks:785g
  • CB Index:58
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  • Company Name:Changzhou Red Sun Pharmaceutical Co., Ltd.
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  • Company Name:Beijing Jingzi Pharmaceutical Technology Co., Ltd.
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  • Products Intro:Product Name:Diquafosol tetrasodium; Diquafosol tetrasodium impurity; Diquafosol tetrasodium intermediate; P1,P4-Diuridine 5'-tetraphosphate tetrasodium salt
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    Purity:99% HPLC Package:10mg;100mg;1kg
  • CB Index:58
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  • Company Name:Hangzhou Hua Zhe Biological Medicine Co., LTD
  • Tel:0571-5683-8096 17302275155
  • Products Intro:Product Name:INS 365
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    Purity:98%HPLC Package:5KG;1KG
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  • Company Name:Hubei Enxing Biotechnology Co., Ltd
  • Tel: 16621771607
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    Purity:99 Package:1kg/RMB 20;1kg1kg
  • CB Index:58
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  • Company Name:S.Z. PhyStandard Bio-Tech. Co., Ltd.
  • Tel:0755-4000505016 13380397412
  • Products Intro:Product Name:Diquafosol Tetrasodium Salt
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    Purity:99% HPLC Package:10mg;25mg;50mg;100mg
  • CB Index:50
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  • Company Name:Nanjing Sunlida Biological Technology Co., Ltd.
  • Tel:025-57798810
  • Products Intro:CAS:211427-08-6
    Purity:98% Package:1g;5g;25g;100g
  • CB Index:55
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  • Company Name:TargetMol Chemicals Inc.
  • Tel:021-021-33632979 15002134094
  • Products Intro:Product Name:Diquafosol tetrasodium
    CAS:211427-08-6
    Purity:99.97% Package:1mg/RMB 256;2mg/RMB 365;5mg/RMB 592
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