zerumbone
471-05-6 Basic informationMore
- Product Name:zerumbone
- Synonyms: zerumbone (2E,6E,10E)-2,6,9,9-Tetramethyl-2,6,10-cycloundecatrien-1-one ZeruMbone (6CI,7CI) (2E,6E,10E)-2,6,9,9-tetramethylcycloundeca-2,6,10-trien-1-one GIHNTRQPEMKFKO-SKTNYSRSSA-N 2,6,10-Cycloundecatrien-1-one, 2,6,9,9-tetramethyl-, (2E,6E,10E)- Zingiber zerumbe extract (2E,6E,10E)-2,6,9,9-Tetramethylcycloundeca-2,6,10-trienone
- CAS:471-05-6
- MF:C15H22O
- MW:218.33
- EINECS:
- Mol File:471-05-6.mol
USE
Zerumbone is isolated from the rhizomes of the wild ginger Zingiber zerumbet. It isfound to suppress the proliferation of breast cancer and colon cancer cells and alsoto prevent initiation and promotion of skin cancer in mice. It also suppresses theNF-κB activation and its sequential suppression of IκBα kinase activity, IκBαphosphorylation, IκBα degradation, p65 phosphorylation, nuclear translocation,and acylation. It downregulates the NF-κB-regulated gene products like FLIP, cyclinD1, TRAF1, COX2, Bfl-1/A1, MMP-9, Bcl-xL, ICAM-1, Bcl-2, c-myc, XIAP,survivin, IAP1, and IAP2, and thus, it potentiates apoptosis (Murakami et al. 2002;Sakinah et al. 2007).
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- Company Name:Nanjing bingcheng Biotechnology Co., Ltd.
- Tel:18805194892; 18805194892
- Products Intro:Product Name:Zerumbone
CAS:471-05-6
Purity:98% Package:1kg;2kg;5kg - CB Index:58
- Related Information:Catalog(157)
- Company Name:Nanjing Chemlin Chemical Co., Ltd
- Tel:025-83697070
- Products Intro:Product Name:Zerumbone
CAS:471-05-6
Purity:98% Package:1mg; 5mg; 50mg; 500mg; 5g; 50g - CB Index:64
- Related Information:Catalog(19179)
- Company Name:Chengdu Biopurify Phytochemicals Ltd.
- Tel:+86-028-82633397 18982077548
- Products Intro:Product Name:Zerumbone
CAS:471-05-6
Purity:>95%,98%,99% Package:From mgs to grams,up to Kgs.Inquire for Bulk scale. - CB Index:60
- Related Information:Catalog(2376)
- Company Name:Shanghai Tauto Biotech Co., Ltd.
- Tel:021-51320588
- Products Intro:Product Name:ZeruMbone
CAS:471-05-6
Purity:NLT 95% HPLC Package:10Mg;20Mg;50Mg;100Mg to graMs.Not More than tens of graMs. Remarks:Z1970 More... - CB Index:66
- Related Information:Catalog(3989)
- Company Name:TargetMol Chemicals Inc.
- Tel:021-021-33632979 15002134094
- Products Intro:Product Name:zerumbone
CAS:471-05-6
Purity:99.75% Package:1mg/RMB 185;5mg/RMB 397;10mg/RMB 583 - CB Index:58
- Related Information:Catalog(7783)
- Company Name:Sichuan Wei Keqi Biological Technology Co., Ltd.
- Tel:028-81700200 18116577057
- Products Intro:Product Name:Zerumbone
CAS:471-05-6
Purity:GC>=98% Package:5mg;10mg;20mg;50mg;100mg;200mg;500mg;1g - CB Index:56
- Related Information:Catalog(7887)