SUBSTANCE P
33507-63-0 Basic informationMore
- Product Name:SUBSTANCE P
- Synonyms: ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2 H2N-ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET H-ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2 SUBSTANCE P, F & D VERSION OF S6883*ACET ATE (2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-N-[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]pentanediamide SUBSTANCE P (HUMAN, BOVINE, RAT, MOUSE) SUBSTANCE P BOVINE SUBSTANCE P, [D-ARG1, D-PRO2, D-TRP7,9, LEU11]
- CAS:33507-63-0
- MF:C63H98N18O13S
- MW:1347.63
- EINECS:251-545-8
- Mol File:33507-63-0.mol
-
USE
Substance P is a polypeptide consisting of 11 amino acidresidues. It has been implicated in the transmission of“painful” sensory information through the spinal cord tohigher centers in the central nervous system. Substance Pis localized in the primary afferent sensory fibers. Other pharmacologicaleffects are vasodilatation, stimulation of smoothmuscles, stimulation of salivary secretion, and diuresis. In addition,this neuropeptide contributes to some inflammatory responses.Approximately 50% of the known neuropeptides aresynthesized as biologically inactive glycine extended precursorsthat require a carboxy-terminal posttranslational amidationfor biological activity. Amidation enzymes are responsiblefor the conversion of the carboxyl group of the neuropeptide tothe corresponding amide group and include the two amidatingenzymes peptidylglycine α-monooxygenase (PAM) and peptidylamidoglycolatelyase (PGL), which work sequentially toproduce the inflammatory neuropeptide Substance P from aninactive precursor peptide. Much research is being performedto exploit this mechanism of inflammation.
Lastest Price from SUBSTANCE P manufacturers
- SUBSTANCE P
-
- US $27.00 /box
- CAS:33507-63-0
- Min. Order: 1box
- Purity: 99%
- Supply Ability: 20000box
- 2024-05-15
- SUBSTANCE P
-
- US $0.00-0.00/kg
- CAS:33507-63-0
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1Ton
- 2022-10-11
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- Company Name:Hangzhou Peptidego Biotech Co.,Ltd.
- Tel:0571-87213919
- Products Intro:Product Name:substance P
CAS:33507-63-0
Purity:98% Package:1mg;5mg;10mg;50mg;100mg,1g or according to customer's detail requirement. Remarks:1g - CB Index:58
- Related Information:Catalog(6526)
- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:Substance P
CAS:33507-63-0
Package:1Mg,5Mg More... - CB Index:76
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- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:Substance P
CAS:33507-63-0
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
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- Company Name:Shanghai Hanhong Scientific Co.,Ltd.
- Tel:021-54306202 13764082696
- Products Intro:Product Name:Substance P
CAS:33507-63-0
Remarks:24P01 More... - CB Index:64
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- Company Name:Cellmano Biotech Limited
- Tel:0551-65326643 18156095617
- Products Intro:Product Name:Substance P
CAS:33507-63-0
Purity:98% HPLC Package:5Mg;10Mg;1g More... - CB Index:55
- Related Information:Catalog(1011)