Pipemidic acid

• Product Name:Pipemidic acid
• Synonyms: 8-ETHYL-5,8-DIHYDRO-5-OXO-2-[1-PIPERAZINYL]PYRIDO[2,3-D]-PYRIMIDINE-6-CARBOXYLIC ACID LABOTEST-BB LT00772244 PIPEMIDIC ACID 1489rb pipemid piperamicacid pipram pyrido(2,3-d)pyrimidine-6-carboxylicacid,5,8-dihydro-8-ethyl-5-oxo-2-(1-piper
• CAS:51940-44-4
• MF:C14H17N5O3
• MW:303.32
• EINECS:257-530-2
• Mol File:51940-44-4.mol
• 

An orally administered pyridopyrimidine derivative with a 7-piperazinyl moiety. The piperazinyl moiety at C-7 increases in-vitro activity against Ps. aeruginosa. Pipemidic acid is inactive against Gram-positive bacteria or anaerobes <br/> It is well absorbed orally. The drug is rapidly metabolized, primarily to acetyl, formyl and oxo derivatives, which exhibit much reduced antibacterial activity. It is eliminated in the urine, 50–85% of a dose appearing over the first 24 h, less than 2% as inactive metabolites. Non-renal clearance accounts for 10–40% of a dose in the young, rising to 40–70% in elderly subjects, thereby compensating for possible renal insufficiency. No dosage adjustment is necessary in patients with mild renal insufficiency. Some of the drug is eliminated in the bile and a significant portion appears in the feces.<br/> Nausea and vomiting are common; dizziness, weakness and grand mal seizures have been observed, principally in the elderly. A number of reactions have been sufficiently severe to require discontinuation of therapy. Clinical use is restricted to urinary tract infections.

• Pipemidic acid
• 
• US $40.00 /kg
• CAS:51940-44-4
• Min. Order: 1kg
• Purity: 0.99
• Supply Ability: 10 tons
• 2024-10-25

• Pipemidic acid
• 
• US $0.00-0.00/g
• CAS:51940-44-4
• Min. Order: 1g
• Purity: 99%
• Supply Ability: 100000tons
• 2023-11-03

• Company Name:Hubei widely chemical technology Co., Ltd.
• Tel:027-83991130 18627774460
• Products Intro:Product Name:Pipemidic acid
  CAS:51940-44-4
  Purity:99.9% Package:1G 50G 1KG 25KG More...
• CB Index:58
• Related Information:Catalog(1879)

• Company Name:XiaoGan ShenYuan ChemPharm co,ltd
• Tel: 15527768850
• Products Intro:CAS:51940-44-4
  More...
• CB Index:52
• Related Information:Catalog(8836)

• Company Name:Hunan Hui Bai Shi Biotechnology Co., Ltd.
• Tel:0731-85526065 13308475853
• Products Intro:Product Name:Pipemidic acid
  CAS:51940-44-4
  Purity:98% Package:10g;50g
• CB Index:62
• Related Information:Catalog(4554)

• Company Name:Shanghai Aladdin Bio-Chem Technology Co.,LTD
• Tel:400-400-6206333 18521732826
• Products Intro:Product Name:Pipemidic acid
  CAS:51940-44-4
  Purity:98% Package:10g/RMB 519.90;50g/RMB 1784.90;250g/RMB 6076.90 More...
• CB Index:65
• Related Information:Catalog(25003)