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138890-62-7

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138890-62-7 Basic informationMore
USE
Brinzolamide eye drops (BrinzolamideEye Drops) is currently a good drug in the treatment of ocular hypertension and open-angle glaucoma remission within elevated intraocular pressure. In April 1998, it had entered into market for the first time in the United States, and has currently entered into market in nearly 30 countries. It was approved for import in China in 2002. It can be as a single drug treatment way for patients to whom β-blockers is ineffective or is contraindicated or used as a co-cure treatment drug together with β-blocker. Its brand name is Azopt. <br/> Brinzolamide eye drops is a sulfa drug, although used as eye drops, but can still be absorbed systemically. Therefore, adverse reactions of sulfa drugs may still occur in the eye drops with time. If severe adverse reactions or allergies occur, you should immediately stop using eye-drops.<br/> For patients subject to oral administration of carbonic anhydrase inhibitors or eye-drop of Azpot, there may be known systemic adverse reactions which are related with carbonic anhydrase inhibition. There have been no studies concerning the co-orally administration of carbonic anhydrase inhibitor and Azopt, thus it is not recommended to use both drugs in combination. Currently there is only limited experience on brinzolamide’s treatment of pseudo-capsular exfoliative and pigmentary glaucoma. In the combination therapy of glaucoma, people mainly evaluate the effects of brinzolamide and timolol. Therefore, information on joint use and other anti-glaucoma drugs is limited.<br/> There have been no studies on the effects of brinzolamide eye drops in patients with acute angle-closure glaucoma and severe renal impairment. Owing to that the product and most of its major metabolites are mainly excreted by the kidney, so those two kinds of patients are not recommended.<br/> Benzalkonium chloride is a commonly used ophthalmic preservative, and it has been reported to cause the punctate keratopathy or (and) ulcerative keratopathy. Azopt contains benzalkonium chloride as a preservative. It can be absorbed by soft contact lenses so it is necessary to wear contact lens only at 15 minutes after being subject to Brinzolamide eye drops. It is not allowed to apply its eye-drop at the same time of wearing contact lenses.<br/> Patients of diabetics, patients with dry eye, corneal lesion need to be closely observed. Pregnant and lactating women or children less than 18 years-old should use with caution.<br/> The above information is edited by the Chemicalbook of Dai Xiongfeng.
Lastest Price from Brinzolamide manufacturers
  • Brinzolamide
  • US $10.00 /KG
  • CAS:138890-62-7
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 20 tons
  • 2021-11-08
  • Brinzolamide
  • US $35.00 /g
  • CAS:138890-62-7
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 1000KG
  • 2021-11-02

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