lubiprostone

• Product Name:lubiprostone
• Synonyms: (2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-heptanoic acid Prostan-1-oic acid, 11,15-epoxy-16,16-difluoro-15-hydroxy-9-oxo-, (11alpha,15R)- Spi 0211 Unii-7662kg2R6k (2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-h 7-((1R,2R,3R)-2-(4,4-difluoro-3-oxooctyl)-3-hydroxy-5-oxocyclopentyl)heptanoic acid AMitiza Lubiprostone 7-((2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoic acid
• CAS:333963-40-9
• MF:C20H32F2O5
• MW:390.46
• EINECS:1312995-182-4
• Mol File:333963-40-9.mol
• 

Chronic constipation is an affliction affecting 4–5 million Americans alone. When no specific cause is identified, it is classified as idiopathic. Dietary and lifestyle modifications are the first-line conventional approaches followed by the administration of laxatives. Unfortunately, chronic idiopathic constipation is frequently refractory to traditional therapy; thus, the need for novel agents exists. Lubiprostone is a bicyclic fatty acid with a novel mechanism of action. Without affecting sodium and potassium ion concentrations, lubiprostone activates intestinal chloride ion channels, thereby, increasing intestinal water secretion and intestinal fluid chloride ion concentration. In basolateral membranepermeabilized T84 gastrointestinal epithelial cells under chloride gradient conditions, lubiprostone concentration-dependently increased short-circuit current with an EC50 of approximately 20 nM.

• Lubiprostone
• 
• US $0.00-0.00/G/Bag
• CAS:333963-40-9
• Min. Order: 1G/Bag
• Purity: 99% up
• Supply Ability: 2 tons
• 2025-01-20

• Lubiprostone
• 
• US $0.00 /g
• CAS:333963-40-9
• Min. Order: 1g
• Purity: More Than 99%
• Supply Ability: 100kg/Month
• 2025-01-13

• Company Name:Shanghai finete Pharmaceutical Co., Ltd.
• Tel:021-021-00000000 18221039705
• Products Intro:Product Name:Lubiprostone
  CAS:333963-40-9
  Purity:99.5% HPLC Package:1g; 10g; 100g ;500g; More...
• CB Index:58
• Related Information:Catalog(208)

• Company Name:Nanjing Vcare PharmaTech Co., Ltd
• Tel:025-58741518 13327700685
• Products Intro:Product Name:7-((1R,2S)-2-(4,4-difluoro-3-oxooctyl)-5-oxocyclopent-3-en-1-yl)heptanoic acid
  CAS:333963-40-9
  Purity:99 Package:1g
• CB Index:58
• Related Information:Catalog(505)

• Company Name:Huigen Biotech (Shanghai) Co., Ltd.
• Tel:13761582449; 13761582449
• Products Intro:Product Name:Lubiprostone
  CAS:333963-40-9
  Purity:98% Package:kg
• CB Index:58
• Related Information:Catalog(189)

• Company Name:Hubei Lingyan Biotechnology Co., Ltd
• Tel:027-59304846 13297025796
• Products Intro:Product Name:lubiprostone
  CAS:333963-40-9
  Purity:99% Package:20g/RMB 1290;200g1000g
• CB Index:58
• Related Information:Catalog(60)

• Company Name:Jinan Junnuo Trading Co., LTD
• Tel: 13345898948
• Products Intro:Product Name:lubiprostone
  CAS:333963-40-9
  Purity:99+ Package:1G;10G
• CB Index:58
• Related Information:Catalog(116)

• Company Name:Chemvon Biotechnology Co., Ltd
• Tel:021-50790412
• Products Intro:Product Name:Lubiprostone
  CAS:333963-40-9
  Purity:>=98% Package:1G/0.00; More...
• CB Index:57
• Related Information:Catalog(371)

• Company Name:Chembest Research Laboratories Limited
• Tel:+86-21-20908456
• Products Intro:Product Name:Lubiprostone
  CAS:333963-40-9
  Remarks:C13836 More...
• CB Index:61
• Related Information:Catalog(6005)