curvularin
10140-70-2 Basic informationMore
- Product Name:curvularin
- Synonyms: curvularin 2H-3-Benzoxacyclododecin-2,10(1H)-dione, 4,5,6,7,8,9-hexahydro-11,13-dihydroxy-4-methyl-,(4S)- S-Curvularin, NSC 166071 (S)-Curvularin (-)-Curvularin
- CAS:10140-70-2
- MF:C16H20O5
- MW:292.33
- EINECS:
- Mol File:10140-70-2.mol
-
USE
Curvularin is a 12-membered macrocyclic lactone incorporating a resorcinyl moiety, produced by a number of fungal species, including Curvularia, Penicillium and Alternaria. Curvularin exhibits a distinctly different biological profile to the structurally similar resorcylic acid lactones such as the zearalenones, radicicol and LL Z1640-2. Curvularin inhibits cell division by disrupting mitotic spindle formation and is known to be phytotoxic. More recent investigations have shown that curvularin is a highly selective transcription-based inhibitor of iNOS-dependent NO production, acting on the Janus tyrosine kinase-STAT pathway. This action offers an approach to the development of drugs inhibiting iNOS overproduction associated with NO pathophysiology.
Browse by Nationality 10140-70-2 Suppliers >Global suppliers
Beijing (9) Shanghai (13) Sichuan (2) Guangdong (5) Zhejiang (3) Fujian (2) Hubei (2) Henan (1) Anhui (1) Jiangsu (2) Shaanxi (2) Yunnan (2) Other (2) Member (46) All (46)
Please select the suppliers
Recommend You Select Member Companies
Recommend You Select Member Companies
- Company Name:Shanghai EFE Biological Technology Co., Ltd.
- Tel:021-65675885 18964387627
- Products Intro:Product Name:Curvularin
CAS:10140-70-2
Purity:98% Package:1mg;5mg More... - CB Index:58
- Related Information:Catalog(9806)
- Company Name:Lynnchem
- Tel:86-(0)29-85992781 17792393971
- Products Intro:Product Name:curvularin
CAS:10140-70-2
Purity:>99% by HPLC Package:1mg;5mg More... - CB Index:58
- Related Information:Catalog(4587)
- Company Name:Shenzhen Polymeri Biochemical Technology Co., Ltd.
- Tel:+86-400-002-6226 +86-13028896684;
- Products Intro:Product Name:Curvularin
CAS:10140-70-2
More... - CB Index:58
- Related Information:Catalog(57412)
- Company Name:Career Henan Chemica Co
- Tel:+86-0371-86658258 +8613203830695
- Products Intro:Product Name:curvularin
CAS:10140-70-2
Purity:Min98% HPLC/GC Package:1KG;1USD - CB Index:58
- Related Information:Catalog(30240)
- Company Name:ChemeGen(Shanghai) Biotechnology Co.,Ltd.
- Tel: 18818260767
- Products Intro:Product Name:Curvularin
CAS:10140-70-2
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g - CB Index:58
- Related Information:Catalog(11217)
- Company Name:BioBioPha Co., Ltd.
- Tel:0871-65217109
- Products Intro:Product Name:Curvularin
CAS:10140-70-2
Purity:98.0% Package:5mg; 10mg; 20mg - CB Index:58
- Related Information:Catalog(1388)
- Company Name:Shaanxi Dideu Medichem Co. Ltd
- Tel:029-81145920 13259709322
- Products Intro:Product Name:curvularin
CAS:10140-70-2
Purity:98% - CB Index:58
- Related Information:Catalog(10009)