MACROLIDES
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- Product Name:MACROLIDES
- Synonyms: MACROLIDES
- CAS:
- MF:
- MW:0
- EINECS:
- Mol File:Mol File
USE
Macrolides are generally safe and serious adverse events are rare. A notable exception is erythromycin estolate, which is hepatotoxic and may cause severe hepatitis, probably as a result of the mixture of lauryl sulfate and the 2′-propionyl ester. Gastrointestinal complaints (nausea, vomiting, abdominal pain or, less frequently, diarrhea) are most common; they present a problem mainly with erythromycin doses higher than those recommended and are partly due to a hemiketal degradation product that acts on motilin, an intestinal endopeptide.<br/> The semisynthetic 14- and 15-membered-ring macrolides are more acid stable than erythromycin A and are better tolerated.
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- Company Name:A.T.CHEMICAL
- Tel:0755-86655561 81899190
- Products Intro:
- CB Index:51
- Related Information:Catalog(6594)