Tolmetin

• Product Name:Tolmetin
• Synonyms: 1-Methyl-5-p-toluoylpyrrole-2-acetic acid 5-[(p-Tolyl)carbonyl]-1-methylpyrrole-2-acetic acid McN 2559 1-Methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetic acid 1-Methyl-5-(p-toluoyl)-1H-pyrrole-2-acetic acid C07149 2-(1-Methyl-5-(4-Methylbenzoyl)-1H-pyrrol-2-yl)acetic acid 2-{1-Methyl-5-[(4-Methylphenyl)carbonyl]-1H-pyrrol-2-yl}acetic acid
• CAS:26171-23-3
• MF:C15H15NO3
• MW:257.28
• EINECS:247-497-2
• Mol File:26171-23-3.mol
• 

Tolmetin sodium (Tolectin), is an arylacetic acid derivativewith a pyrrole as the aryl group. This drug is well absorbed and has a relatively short plasma half-life (1 hour). It is recommendedfor use in the management of acute and chronicRA. Its efficacy is similar to aspirin and indomethacin, butwith less frequency of the adverse effects and tinnitus associatedwith aspirin. It does not potentiate coumarin-likedrugs nor alter the blood levels of sulfonylureas or insulin.However, tolmetin, and especially its closely related drug,zomepirac (i.e., with a p-chlorobenzoyl group and an additionalmethyl group on the pyrrole ring), can produce a rarebut fatal anaphylactic reaction because of irreversible bindingof their unstable acyl glucuronides. Zomepirac waswithdrawn from market because it is eliminated only via theester-type, acyl glucuronide. It is possible that tolmetin isless toxic in this regard because it undergoes additional hepaticbenzylic hydroxylation via its p-methyl group and isexcreted as its stable ether glucuronide.

• Tolmetin
• 
• US $50.00 /kg
• CAS:26171-23-3
• Min. Order: 1kg
• Purity: 99.9%
• Supply Ability: 10000MT
• 2023-09-07

• Tolmetin
• 
• US $0.00 /KG
• CAS:26171-23-3
• Min. Order: 1KG
• Purity: 99%
• Supply Ability: 50000KG/month
• 2023-07-26

• Company Name:Zhangjiagang huamao Fine chemical Co.,Ltd.
• Tel:0512-58327208; 13962221965
• Products Intro:Product Name:Tolmetin; 1H-Pyrrole-2-aceticacid, 1-methyl-5-(4-methylbenzoyl)-
  CAS:26171-23-3
  Purity:98% HPLC Package:5Kg;25Kg More...
• CB Index:58
• Related Information:Catalog(34)

• Company Name:Shanghai Hanhong Scientific Co.,Ltd.
• Tel:021-54306202 13764082696;
• Products Intro:Product Name:Tolmetin
  CAS:26171-23-3
  Purity:95% Remarks:AB04578 More...
• CB Index:64
• Related Information:Catalog(42982)

• Company Name:TargetMol Chemicals Inc.
• Tel:021-33632979 15002134094
• Products Intro:Product Name:NSC-226572;NSC-226572;Methyiin; pyrolyzate;NSC 226572;NSC226572
  CAS:26171-23-3
  Package:10 mg;25 mg More...
• CB Index:58
• Related Information:Catalog(7934)

• Company Name:Shanghai Chainpharm Bio-medical Technology Co., Ltd.
• Tel:021-61727342 13611721451
• Products Intro:Product Name:TolMetin
  CAS:26171-23-3
  Purity:97%HPLC Package:1g,5g,10g,25g,100g,500g,1kg,25kg or on request More...
• CB Index:58
• Related Information:Catalog(931)