Satraplatin
129580-63-8 Basic informationMore
- Product Name:Satraplatin
- Synonyms: bis(acetato-o)amminedichloro(cyclohexanamine)-pt platinum (lv) cis-dichloro-trans-bis(acetato-o)ammine(cyclohexanamine) SATRAPLATIN JM 216 Bis-acetatoamminedichlorocyclohexylamine platinum(iv) C081294 Platinum, bis(acetato-o)amminedichloro(cyclohexanamine)-, (oc-6-43)- Satraplatin(JM216)
- CAS:129580-63-8
- MF:C10H20Cl2N2O4Pt
- MW:498.26
- EINECS:
- Mol File:129580-63-8.mol
-
USE
Satraplatin (JM216, cis,trans,cis-[PtCl2(OAc)2(NH3)(C6H5NH2)]) is a Pt(IV) or Pt4+ complex, which is
active by oral administration, as it is more hydrophobic than cisplatin. This form of administration is very
attractive because of the convenience and freedom it provides to the patient. Satraplatin also has a milder toxicity
profile and is shows no cross-resistance with cisplatin. Satraplatin in combination with prednisone has
completed phase III clinical trials against hormone-refractory prostate cancer. The results were very encouraging,
but the overall survival rate did not improve significantly enough. As a result, the fast-track approval
of the FDA was not granted.<br/>Structurally, satraplatin consists of a Pt(IV) centre, which is coordinated by six ligands forming a close to octahedral geometry. In general, octahedral Pt(IV) complexes (low-spin d6) are much more kinetically inert than square planar Pt(II) complexes.
Lastest Price from Satraplatin manufacturers
- Satraplatin
-
- US $0.00 /g
- CAS:129580-63-8
- Min. Order: 10g
- Purity: 98%-102%
- Supply Ability: 100g
- 2024-11-02
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- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:Satraplatin
CAS:129580-63-8
Purity:98% HPLC Package:1g;5g;25g;100g More... - CB Index:69
- Related Information:Catalog(15839)
- Company Name:Chembest Research Laboratories Limited
- Tel:+86-21-20908456
- Products Intro:Product Name:Satraplatin(JM-216)
CAS:129580-63-8
Purity:99% Package:1g Remarks:C14145 More... - CB Index:61
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- Company Name:Wuhan Fortuna Chemical Co., Ltd
- Tel:027-59207852 13308628970
- Products Intro:Product Name:Satraplatin
CAS:129580-63-8
Purity:98% Package:1kg/ - CB Index:58
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- Company Name:Finetech Industry Limited
- Tel:027-87465837 19945049750
- Products Intro:Product Name:Satraplatin
CAS:129580-63-8
Purity:98% Package:1g;10g;25g;500g;1kg - CB Index:58
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- Company Name:Hubei Jusheng Technology Co.,Ltd
- Tel:027-59599241 18871490274
- Products Intro:Product Name:Satraplatin
CAS:129580-63-8
Purity:99% HPLC Package:25KG;200KG;5KG;1KG;1T More... - CB Index:58
- Related Information:Catalog(9958)