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THROMBOMODULIN

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USE
Recombinant thrombomodulin, an anticoagulant, was approved and launched in Japan for the intravenous treatment of DIC. DIC is a blood clotting disorder in which the blood coagulation system becomes overactive, leading to blockage of capillaries, ischemia and other damage to vascular endothelial cells, and organ damage. Concurrently, the use and subsequent depletion of platelets and coagulation proteins resulting from the ongoing coagulation may induce severe bleeding. DIC frequently occurs as a complication of malignant tumors and infections. Bleeding is typically the presenting symptom in patients with DIC, a factor that can complicate decisions about treatment. Thrombomodulin is an endothelial cell membrane glycoprotein that neutralizes thrombin pro-coagulant activity and accelerates the thrombin-catalyzed activation of anticoagulant protein C, thus allowing potential use in the treatment of thrombotic disorders such as DIC.

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  • Company Name:Sigma-Aldrich
  • Tel:021-61415566 800-8193336
  • Products Intro:Product Name:Thrombomodulin
    Purity:>=98% (HPLC); >=98% (SDS-PAGE) Package:10μg Remarks:SRP3172 More...
  • CB Index:80
  • Related Information:Catalog(51471)
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  • Company Name:Shanghai Huzhen Industrial Co., LTD
  • Tel:021-60345367 13916550749
  • Products Intro:Product Name:Thrombomodulin
    Purity:> 99% Package:50ul/RMB 1138;100ul/RMB 1880;200ul/RMB 2900 Remarks:CD 141; CD141; CD141 antigen; Fetomodulin; THBD; THRM; TM; AHUS 6; AHUS6; BDCA 3; BDCA3; THPH12; TRBM_HUMAN.
  • CB Index:58
  • Related Information:Catalog(9965)
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  • Company Name:Shanghai Tongwei Biotechnology Co., Ltd
  • Tel:021-66980655
  • Products Intro:Product Name:Thrombomodulin
  • CB Index:58
  • Related Information:Catalog(6378)
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