Zalcitabine
7481-89-2 Basic informationMore
- Product Name:Zalcitabine
- Synonyms: 4-AMINO-1-[(2R,5S)-5-(HYDROXYMETHYL)OXOLAN-2-YL]PYRIMIDIN-2-ONE ZALCITABINE 1-(2',3'-DIDEOXY-BETA-RIBOFURANOSYL)CYTOSINE 2',3'-Dideoxy-D-cytidine 2'',3''-DIDEOXYCYTIDINE(ZALCITABINE) Cytidine, 2',3'-dideoxy- (8CI, 9CI) D 2C NSC 606170
- CAS:7481-89-2
- MF:C9H13N3O3
- MW:211.22
- EINECS:620-762-3
- Mol File:7481-89-2.mol
-
USE
Zalcitabine, 2',3'-dideoxycytidine or ddCyd, is an analog ofcytosine that demonstrates activity against HIV-1 and HIV-2,including strains resistant to AZT. The potency (in peripheralblood mononuclear cells) is similar to that of AZT, but thedrug is more active in populations of monocytes andmacrophages as well as in resting cells.<br/>The oral bioavailability of zalcitabine is over 80% in adultsand less in children.The major dose-limiting side effect isperipheral neuropathy, characterized by pain, paresthesias,and hypesthesia, beginning in the distal lower extremities.These side effects are typically evident after several months oftherapy with zalcitabine. A potentially fatal pancreatitis is anothertoxic effect of treatment with ddC. The drug has beenapproved for the treatment of HIV infection in adults with advanceddisease who are intolerant to AZT or who have diseaseprogression while receiving AZT. ddC is combined with AZTfor the treatment of advanced HIV infection.
Lastest Price from Zalcitabine manufacturers
- Zalcitabine
-
- US $30.00 /kg
- CAS:7481-89-2
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 3000kg
- 2025-01-19
- Zalcitabine
-
- US $0.00-0.00/KG
- CAS:7481-89-2
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 500000kg
- 2024-10-28
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- Company Name:Maanshan geneyan biotech Co.,LTD
- Tel: 18913822354
- Products Intro:Product Name:Zalcitabine
CAS:7481-89-2
Purity:99% Package:100g,1kg,10kg More... - CB Index:58
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:2',3'-Dideoxycytidine
CAS:7481-89-2
Purity:98.0%(LC&T) Package:1G More... - CB Index:76
- Related Information:Catalog(96815)
- Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel:021-61259108 18621169109
- Products Intro:Product Name:2',3'-Dideoxycytidine
CAS:7481-89-2
Purity:>98.0%(LC)(T) Package:1g Remarks:D3581 More... - CB Index:62
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- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:Zalcitabine
CAS:7481-89-2
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
- Related Information:Catalog(15839)
- Company Name:Hongene Biotech Corporation
- Tel:021-64757213
- Products Intro:Product Name:2',3'-ddC; 2', 3'-Dideoxycytidine/Zalcitabine
CAS:7481-89-2
Purity:HPLC >=99% Package:G; KG More... - CB Index:61
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- Company Name:Chembest Research Laboratories Limited
- Tel:+86-21-20908456
- Products Intro:Product Name:Zalcitabine(2'-3'-dideoxycytidine, ddC)
CAS:7481-89-2
Remarks:C14359 More... - CB Index:61
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