TetroMycin B
180027-84-3 Basic informationMore
- Product Name:TetroMycin B
- Synonyms: TetroMycin B 18H-16a,19-Metheno-16aH-benzo[b]naphth[2,1-j]oxacyclotetradecin-18,20(1H)-dione, 2,3,4,4a,6a,9,10,12a,15,16,20a,20b-dodecahydro-4,21-trihydroxy-1,6,7,11,12a,14,15,20a-octamethyl-, (1S,4S,4aS,6aR,7E,11E,12aR,15R,16aS,20aS,20bR)- (9CI)
- CAS:180027-84-3
- MF:C34H46O5
- MW:534.72604
- EINECS:
- Mol File:180027-84-3.mol
-
USE
Tetromycin B is an unusual tetronic acid, structurally related to kijanimicin, chlorothricin, saccharocarcin, tetrocarcin and versipelostatin. Tetromycin B has pronounced activity against antibiotic susceptible and resistant Gram positive bacteria including MRSA. Limited availability has restricted further investigation of this metabolite in the literature. Several members of this class have received considerable literature focus. Versipelostatin inhibits transcription from the promoter of GRP78, a gene that is activated as part of a stress signalling pathway under glucose deprivation resulting in unfolded protein response (UPR). The UPR-inhibitory action is seen only in conditions of glucose deprivation and causes selective and massive killing of the glucose-deprived cells. Tetrocarcin A appears to target the phosphatidylinositide-3'-kinase/Akt signalling pathway.
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- Company Name:Lynnchem
- Tel:86-(0)29-85992781 17792393971
- Products Intro:Product Name:TetroMycin B
CAS:180027-84-3
Purity:>99% by HPLC Package:1mg;5mg More... - CB Index:58
- Related Information:Catalog(4587)
- Company Name:Shenzhen Polymeri Biochemical Technology Co., Ltd.
- Tel:+86-400-002-6226 +86-13028896684;
- Products Intro:Product Name:Tetromycin B
CAS:180027-84-3
More... - CB Index:58
- Related Information:Catalog(56354)
- Company Name:TargetMol Chemicals Inc.
- Tel: 4008200310
- Products Intro:Product Name:Tetromycin B
CAS:180027-84-3
Package:500μg/RMB 4460 - CB Index:58
- Related Information:Catalog(24648)
- Company Name:Shanghai Yifei Biotechnology Co. , Ltd.
- Tel:021-65675885 18964387627
- Products Intro:Product Name:Tetromycin B
CAS:180027-84-3
Purity:99% Package:500μg;2.5mg - CB Index:58
- Related Information:Catalog(11975)
- Company Name:Nanjing Shizhou Biology Technology Co.,Ltd
- Tel:025-85560043 15850508050
- Products Intro:Product Name:Tetromycin B
CAS:180027-84-3
Purity:98% Package:10mg 100mg - CB Index:58
- Related Information:Catalog(12007)