JW55

• Product Name:JW55
• Synonyms: JW55 N-(4-((4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-yl)MethylcarbaMoyl)phenyl)furan-2-carboxaMide N-[4-[[4-(4-METHOXYPHENYL)OXAN-4-YL]METHYLCARBAMOYL]PHENYL]FURAN-2-CARBOXAMIDE N-[4-[[[[Tetrahydro-4-(4-methoxyphenyl)-2H-pyran-4-yl]methyl]amino]carbonyl]phenyl]-2-furancarboxamide JW55 N-[4-[[[[Tetrahydro-4-(4-methoxyphenyl)-2H-pyran-4-yl]methyl]amino]carbonyl]phenyl]-2-furancarboxamide JW 55, >=98% N-(4-(((4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-yl)methyl)carbamoyl)phenyl)furan-2-carboxamid Tankyrase1/2 Inhibitor IV, JW55
• CAS:664993-53-7
• MF:C25H26N2O5
• MW:434.48
• EINECS:
• Mol File:664993-53-7.mol
• 

JW-55 is an inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). Activity results in stabilization of Axin2 and increased degradation of β-catenin. JW-55 inhibits the β-catenin signaling pathway. Also shown to decrease canonical Wnt signaling in SW480 and HCT-15 colon carcinoma cell lines. JW-55 reduces cell cycle progression and proliferation in SW480 cells in vitro.

• Company Name:Jingmo (Xiamen) Biotechnology Co., Ltd
• Tel:13621943973; 13621943973
• Products Intro:Product Name:JW55
  CAS:664993-53-7
  Purity:>98% Package:1g, 5g,10g,100g Remarks:15g
• CB Index:58
• Related Information:Catalog(1110)

• Company Name:Olix (Shanghai) Pharmaceutical Technology Co., Ltd
• Tel: 17316404525
• Products Intro:Product Name:JW 55
  CAS:664993-53-7
  Purity:98% HPLC Package:5mg,500mg,1g,100g
• CB Index:58
• Related Information:Catalog(9765)

• Company Name:J & K SCIENTIFIC LTD.
• Tel:010-82848833 400-666-7788
• Products Intro:Product Name:JW-55
  CAS:664993-53-7
  Package:100Mg,10Mg More...
• CB Index:76
• Related Information:Catalog(96815)