Dacomitinib (PF299804)

• Product Name:Dacomitinib (PF299804)
• Synonyms: PF-00299804-03 PF-00299804 DacoMitinib (PF-00299804) DacoMitinib,PF299804 DacoMitinib (PF299804,PF-00299804) PF299804;DACOMITINIB DacoMitinib (PF299804, PF299) (E)-N-(4-((3-chloro-4-fluorophenyl)aMino)-7-Methoxyquizolin-6-yl)-4-(piperidin-1-yl)but-2-eMide
• CAS:1110813-31-4
• MF:C24H25ClFN5O2
• MW:469.94
• EINECS:000-000-0
• Mol File:1110813-31-4.mol
• 

Dacomitibib (Dacomitinib, PF299804) is an effective and irreversible pan-ErbB inhibitor that is most effective in EGFR, with an IC50 of 6 nM. It is also highly effective in NSCLCs that carries EGFR or ERBB2 mutants (against Gefitinib) and EGFR T790M mutant. Phase 2.<br /> Dacomitinib is taken orally once-daily. It is an irreversible inhibitor of HER-1 (EGFR), HER-2 and HER-4 tyrosine kinases. Dacomitinib targets multiple receptors of the HER pathway, whereas currently marketed HER-1 (EGFR) inhibitors for non-small cell lung cancer (NSCLC) target only one receptor in this pathway,developed by Pfizer.

• Dacomitinib
• 
• US $0.00-0.00/kg
• CAS:1110813-31-4
• Min. Order: 1kg
• Purity: 99%，single impurity＜0.1
• Supply Ability: 1 ton
• 2024-11-26

• Dacomitinib（PF299804）
• 
• US $0.00-0.00/g
• CAS:1110813-31-4
• Min. Order: 10g
• Purity: 99% HPLC
• Supply Ability: 1000kg
• 2024-11-26

• Company Name:WuHu Linze pharmaceutical Co.,Ltd.
• Tel:0553-0553-5802116 18356571950
• Products Intro:Product Name:Dacomitinib (PF299804)
  CAS:1110813-31-4
  Purity:99.9 Package:500g More...
• CB Index:58
• Related Information:Catalog(57)

• Company Name:Chembest Research Laboratories Limited
• Tel:+86-21-20908456
• Products Intro:Product Name:Dacomitinib (PF-299804
  CAS:1110813-31-4
  Purity:98%+ HPLC Package:50mg;100mg;500mg;1g;5g;10g Remarks:Biochemical Reagents; Pharmaceutical Intermediates More...
• CB Index:61
• Related Information:Catalog(6005)

• Company Name:TCI (Shanghai) Development Co., Ltd.
• Tel:021-67121386
• Products Intro:Product Name:Dacomitinib
  CAS:1110813-31-4
  Purity:98.0% LC Package:250MG,50MG More...
• CB Index:81
• Related Information:Catalog(24529)

• Company Name:Adamas Reagent, Ltd.
• Tel:400-6009262 16621234537
• Products Intro:Product Name:Dacomitinib
  CAS:1110813-31-4
  Purity:99%+ Package:100mg;250mg;1g;5g
• CB Index:59
• Related Information:Catalog(14103)