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Dacomitinib (PF299804)

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1110813-31-4 Basic informationMore
USE
Dacomitibib (Dacomitinib, PF299804) is an effective and irreversible pan-ErbB inhibitor that is most effective in EGFR, with an IC50 of 6 nM. It is also highly effective in NSCLCs that carries EGFR or ERBB2 mutants (against Gefitinib) and EGFR T790M mutant. Phase 2.<br /> Dacomitinib is taken orally once-daily. It is an irreversible inhibitor of HER-1 (EGFR), HER-2 and HER-4 tyrosine kinases. Dacomitinib targets multiple receptors of the HER pathway, whereas currently marketed HER-1 (EGFR) inhibitors for non-small cell lung cancer (NSCLC) target only one receptor in this pathway,developed by Pfizer.
Lastest Price from Dacomitinib (PF299804) manufacturers
  • Dacomitinib
  • US $0.00 /g
  • CAS:1110813-31-4
  • Min. Order: 100g
  • Purity: 99%min
  • Supply Ability: 1000g
  • 2022-08-15
  • Dacomitinib
  • US $0.00 /KG
  • CAS:1110813-31-4
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 200000pcs
  • 2021-11-15

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  • Company Name:WuHu Linze pharmaceutical Co.,Ltd.
  • Tel:0553-5802116 18356571950
  • Products Intro:Product Name:Dacomitinib (PF299804)
    CAS:1110813-31-4
    Purity:99.9 Package:500g More...
  • CB Index:58
  • Related Information:Catalog(53)
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  • Company Name:Sichuan Qingmu Pharmaceutical Co., Ltd.
  • Tel:28-87827187 15102825326
  • Products Intro:Product Name:Dacomitinib
    CAS:1110813-31-4
    Purity:In-House; HPLC Package:1KG; 5KG;10KG
  • CB Index:60
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  • Company Name:Jurong Coupling Biotechnology Co., Ltd.
  • Tel: 13656108824
  • Products Intro:Product Name:Dacomitinib (PF299804)
    CAS:1110813-31-4
    Package:100g More...
  • CB Index:58
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  • Company Name:Nanjing Jiusi Pharmaceutical Technology Development Co., Ltd.
  • Tel: 13921426630
  • Products Intro:CAS:1110813-31-4
    Purity:99%HPLC Package:5g;25g;100g
  • CB Index:58
  • Related Information:Catalog(94)
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  • Company Name:Wuhan Bo Jin Biotechnology Co.,Ltd.
  • Tel: 18164232327
  • Products Intro:Product Name:Dacomitinib
    CAS:1110813-31-4
    Purity:99% Package:10g/RMB 100;100g500g
  • CB Index:58
  • Related Information:Catalog(67)
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  • Company Name:Chembest Research Laboratories Limited
  • Tel:021-20908456
  • Products Intro:Product Name:Dacomitinib (PF-299804
    CAS:1110813-31-4
    Purity:98%+ HPLC Package:50mg;100mg;500mg;1g;5g;10g Remarks:Biochemical Reagents; Pharmaceutical Intermediates More...
  • CB Index:61
  • Related Information:Catalog(6002)
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