ZOTAROLIMUS
221877-54-9 Basic informationMore
- Product Name:ZOTAROLIMUS
- Synonyms: ZOTAROLIMUS (42S)-42-Deoxy-42-(1H-tetrazol-1-yl)rapamycin A 179578 ABT 578 Rapamycin, 42-deoxy-42-(1H-tetrazol-1-yl)-, (42S)- Unii-H4gxr80ize ZotaroliMus, >90% 42-(1-Tetrazolyl)rapamycin
- CAS:221877-54-9
- MF:C52H79N5O12
- MW:966.21
- EINECS:
- Mol File:221877-54-9.mol
-
USE
Zotarolimus is a semi-synthetic macrocyclic lactone prepared from rapamycin by preparation of the 42-triflate ester, followed by displacement with tetrazole and purification of the two isomeric products. This structural change affords a less bioavailable product, a preferred profile for some applications. Like all tacrolimus analogues, zotarolimus binds to a receptor protein (FKBP12). The complex then binds to mTOR preventing it from interacting with target proteins. Zotarolimus is extensively cited in the literature with over 200 citations.
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:Zotarolimus, 98%
CAS:221877-54-9
Purity:98% Package:25MG;5MG More... - CB Index:76
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- Company Name:Chembest Research Laboratories Limited
- Tel:+86-21-20908456
- Products Intro:Product Name:Zotarolimus (ABT-578
CAS:221877-54-9
Purity:98%+ HPLC Package:50mg;100mg;500mg;1g;5g;10g Remarks:Biochemical Reagents; Pharmaceutical Intermediates More... - CB Index:61
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- Company Name:Dalian Meilun Biotech Co., Ltd.
- Tel:0411-62910999 13889544652
- Products Intro:Product Name:Zotarolimus(ABT-578)
CAS:221877-54-9
Purity:>98%,BR Package:5MG;25MG; Remarks:MB7469 - CB Index:58
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- Company Name:Nanjing Sunlida Biological Technology Co., Ltd.
- Tel:025-57798810
- Products Intro:CAS:221877-54-9
Purity:98% Package:1g;5g;25g;100g - CB Index:55
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- Company Name:ShangHai Caerulum Pharma Discovery Co., Ltd.
- Tel:18149758185 18149758185
- Products Intro:Product Name:ZOTAROLIMUS
CAS:221877-54-9
Purity:98% Package:10mg;100mg;1g;10g;100g;1kg - CB Index:58
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- Company Name:ChemStrong Scientific Co.,Ltd
- Tel:0755-0755-66853366 13670046396
- Products Intro:Product Name:Zotarolimus
CAS:221877-54-9
Purity:95% HPLC Package:10mg;25mg;50mg;100mg More... - CB Index:56
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