Telithromycin
191114-48-4 Basic informationMore
- Product Name:Telithromycin
- Synonyms: (1R,2R,4R,6S,7R,8R,10R,13R,14S)-7-[(2S,3R,4S,6R)-4-Dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-13-ethyl-6-methoxy-2,4,6,8,10,14-hexamethyl-17-[4-(4-pyridin-3-ylimidazol-1-yl)butyl]-12,15-dioxa-17-azabicyclo[12.3.0]heptadecane-3,9,11,16-tetrone KETEK (3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-4-Ethyloctahydro-11-Methoxy-3a,7,9,11,13,15-hexaMethyl-1-[4-[4-(3-pyridinyl)-1H-iMidazol-1-yl]butyl]-10-[[3,4,6-trideoxy-3-(diMethylaMino)-β-D-xylo-hexopyranosyl]oxy]-2H-oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)tetrone HMR 3647 RU 66647 2H-Oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)-tetrone,4-ethyloctahydro-11-Methoxy-3a,7,9,11,13,15-hexaMethyl-1-[4-[4-(3-pyridinyl)-1H-iMidazol-1-yl]butyl]-10-[[3,4,6-trideoxy-3-(diMethylaMino)-b-D-xylo-hexopyranosyl]oxy]-,(3aS,4R,7R,9R,10R,11R,1 TELITHROMYCIN TelithroMycin 90%
- CAS:191114-48-4
- MF:C43H65N5O10
- MW:812
- EINECS:682-750-4
- Mol File:191114-48-4.mol
USE
Telithromycin (Ketek) is an orally bioavailable macrolide.The antibiotic is semisynthetic. Telithromycin is classifiedas a ketolide, and it differs chemically from the macrolidegroup of antibacterials by the lack of α-L-cladinose at 3-position of the erythronolide A ring, resulting in a 3-ketofunction. It is further characterized by imidazolyl andpyridyl rings inked to the macrolide nucleus through a butylchain. The mechanism of action of telithromycin is the sameas that of the macrolide class.<br/>Telithromycin causes a blockade of protein synthesis bybinding to domains II and V of 23S rRNA of the 50S ribosomalsubunit. Because telithromycin binds at domain II,activity against Gram-positive cocci is retained in the presenceof resistance mediated by methylases that alter thedomain V binding site. The antibiotic is also believed to inhibitthe assembly of ribosomes. Resistance to telithromycinoccurs because of riboprotein mutations.
Lastest Price from Telithromycin manufacturers
- Telithromycin
- US $0.00 /G
- CAS:191114-48-4
- Min. Order: 1G
- Purity: 98%min
- Supply Ability: 30kg/month
- 2024-11-22
- Telithromycin
- US $10.50 /KG
- CAS:191114-48-4
- Min. Order: 1KG
- Purity: 99
- Supply Ability: 1 ton
- 2024-10-11
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:TelithroMycin 90%
CAS:191114-48-4
Package:10Mg,1Mg More... - CB Index:76
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- Company Name:Hangzhou Yuhao Chemical Technology Co., Ltd
- Tel:0571-82693216
- Products Intro:CAS:191114-48-4
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- Company Name:Dalian Meilun Biotech Co., Ltd.
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- Products Intro:Product Name:Telithromycin
CAS:191114-48-4
Purity:>98% Package:10mg Remarks:MB1499 More... - CB Index:58
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- Company Name:UHN Shanghai Research & Development Co., Ltd.
- Tel:021-58958002 18930822973
- Products Intro:Product Name:Telithromycin
CAS:191114-48-4
Purity:98% LC-MS Package:10g, 50g, 100g, 1Kg - CB Index:58
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